[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …
Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …
patients, but high rates of a partial response or no response, and the delayed onset of the …
[HTML][HTML] Adolescent obesity: diet quality, psychosocial health, and cardiometabolic risk factors
Obesity is a multifaceted chronic condition with several contributing causes, including
biological risk factors, socioeconomic status, health literacy, and numerous environmental …
biological risk factors, socioeconomic status, health literacy, and numerous environmental …
Childhood and adolescent adversity and cardiometabolic outcomes: a scientific statement from the American Heart Association
Adverse experiences in childhood and adolescence, defined as subjectively perceived
threats to the safety or security of the child's bodily integrity, family, or social structures, are …
threats to the safety or security of the child's bodily integrity, family, or social structures, are …
[HTML][HTML] Ghrelin
Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence …
The brain reward circuitry in mood disorders
SJ Russo, EJ Nestler - Nature reviews neuroscience, 2013 - nature.com
Mood disorders are common and debilitating conditions characterized in part by profound
deficits in reward-related behavioural domains. A recent literature has identified important …
deficits in reward-related behavioural domains. A recent literature has identified important …
[HTML][HTML] The homeostatic force of ghrelin
Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …
information about peripheral nutritional status to the brain, and is essential for protecting …
A standardized protocol for repeated social defeat stress in mice
A major impediment to novel drug development has been the paucity of animal models that
accurately reflect symptoms of affective disorders. In animal models, prolonged social stress …
accurately reflect symptoms of affective disorders. In animal models, prolonged social stress …
Neuropeptides and the microbiota-gut-brain axis
P Holzer, A Farzi - Microbial endocrinology: the microbiota-gut-brain axis …, 2014 - Springer
Neuropeptides are important mediators both within the nervous system and between
neurons and other cell types. Neuropeptides such as substance P, calcitonin gene-related …
neurons and other cell types. Neuropeptides such as substance P, calcitonin gene-related …
Nutritional aspects of depression
Several nutrition, food and dietary compounds have been suggested to be involved in the
onset and maintenance of depressive disorders and in the severity of depressive symptoms …
onset and maintenance of depressive disorders and in the severity of depressive symptoms …