Animal models of atherosclerosis–supportive notes and tricks of the trade
A Gisterå, DFJ Ketelhuth, SG Malin… - Circulation …, 2022 - Am Heart Assoc
Atherosclerotic cardiovascular disease is a major cause of death among humans. Animal
models have shown that cholesterol and inflammation are causatively involved in the …
models have shown that cholesterol and inflammation are causatively involved in the …
[HTML][HTML] Small rodent models of atherosclerosis
Y Zhao, H Qu, Y Wang, W Xiao, Y Zhang… - Biomedicine & …, 2020 - Elsevier
The ease of breeding, low cost of maintenance, and relatively short period for developing
atherosclerosis make rodents ideal for atherosclerosis research. However, none of the …
atherosclerosis make rodents ideal for atherosclerosis research. However, none of the …
Targeting of scavenger receptors stabilin-1 and stabilin-2 ameliorates atherosclerosis by a plasma proteome switch mediating monocyte/macrophage suppression
CP Manta, T Leibing, M Friedrich, H Nolte, M Adrian… - Circulation, 2022 - Am Heart Assoc
Background: Scavenger receptors Stabilin-1 (Stab1) and Stabilin-2 (Stab2) are preferentially
expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating …
expressed by liver sinusoidal endothelial cells. They mediate the clearance of circulating …
The miR‐126‐5p and miR‐212‐3p in the extracellular vesicles activate monocytes in the early stage of radiation‐induced vascular inflammation implicated in …
YY Choi, A Kim, Y Lee, YH Lee, M Park… - Journal of …, 2023 - Wiley Online Library
People exposed to radiation in cancer therapy and nuclear accidents are at increased risk of
cardiovascular outcomes in long‐term survivors. Extracellular vesicles (EVs) are involved in …
cardiovascular outcomes in long‐term survivors. Extracellular vesicles (EVs) are involved in …
CagA+ Helicobacter pylori, Not CagA– Helicobacter pylori, Infection Impairs Endothelial Function Through Exosomes-Mediated ROS Formation
X Xia, L Zhang, H Wu, F Chen, X Liu, H Xu… - Frontiers in …, 2022 - frontiersin.org
Background Helicobacter pylori (H. pylori) infection increases the risk for atherosclerosis,
and ROS are critical to endothelial dysfunction and atherosclerosis. CagA is a major H …
and ROS are critical to endothelial dysfunction and atherosclerosis. CagA is a major H …
Unveiling the oral-gut connection: chronic apical periodontitis accelerates atherosclerosis via gut microbiota dysbiosis and altered metabolites in apoE−/− Mice on a …
G Gan, S Lin, Y Luo, Y Zeng, B Lu, R Zhang… - International Journal of …, 2024 - nature.com
The aim of this study was to explore the impact of chronic apical periodontitis (CAP) on
atherosclerosis in apoE−/− mice fed high-fat diet (HFD). This investigation focused on the …
atherosclerosis in apoE−/− mice fed high-fat diet (HFD). This investigation focused on the …
TNF-α Preconditioning Improves the Therapeutic Efficacy of Mesenchymal Stem Cells in an Experimental Model of Atherosclerosis
Atherosclerosis (AS) is an inflammatory disease involving multiple factors in its initiation and
development. In recent years, the potential application of mesenchymal stem cells (MSCs) …
development. In recent years, the potential application of mesenchymal stem cells (MSCs) …
Apple Polyphenol Extract Ameliorates Atherosclerosis and Associated Cognitive Impairment through Alleviating Neuroinflammation by Weakening TLR4 Signaling …
H Yang, R Song, Y Xie, Q Qian, Z Wu… - Journal of Agricultural …, 2023 - ACS Publications
Although studies have supported the beneficial effects of the ingredients of apple
polyphenol extract (APE), a polyphenol mixture being extracted from whole fresh apples, on …
polyphenol extract (APE), a polyphenol mixture being extracted from whole fresh apples, on …
Gut microbiota may mediate the impact of chronic apical periodontitis on atherosclerosis in apolipoprotein E‐deficient mice
G Gan, R Zhang, B Lu, Y Luo, S Chen… - International …, 2023 - Wiley Online Library
Aim There are growing evidences linking chronic apical periodontitis (CAP) to
atherosclerosis. Gut microbiota is found to be involved in the development of …
atherosclerosis. Gut microbiota is found to be involved in the development of …
Research methods for animal models of atherosclerosis
Y Zhang, M Fatima, S Hou, L Bai… - Molecular medicine …, 2021 - spandidos-publications.com
Atherosclerosis is a chronic inflammatory disease that threatens human health and lives by
causing vascular stenosis and plaque rupture. Various animal models have been employed …
causing vascular stenosis and plaque rupture. Various animal models have been employed …