Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Polymyxins: antibacterial activity, susceptibility testing, and resistance mechanisms encoded by plasmids or chromosomes

L Poirel, A Jayol, P Nordmann - Clinical microbiology reviews, 2017 - Am Soc Microbiol
Polymyxins are well-established antibiotics that have recently regained significant interest
as a consequence of the increasing incidence of infections due to multidrug-resistant Gram …

The global ascendency of OXA-48-type carbapenemases

JDD Pitout, G Peirano, MM Kock… - Clinical microbiology …, 2019 - Am Soc Microbiol
Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

The rapid spread of carbapenem-resistant Enterobacteriaceae

RF Potter, AW D'Souza, G Dantas - Drug Resistance Updates, 2016 - Elsevier
Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now
threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae …

Occurrence of carbapenemase-producing Enterobacteriaceae in a Portuguese river: blaNDM, blaKPC and blaGES among the detected genes

P Teixeira, M Tacão, L Pureza, J Gonçalves… - Environmental …, 2020 - Elsevier
Carbapenems are used as last-resort drugs to treat infections caused by multidrug-resistant
bacteria. Despite the increasing number of reports of carbapenem-resistant …

Multihospital Occurrence of Pan-Resistant Klebsiella pneumoniae Sequence Type 147 with an ISEcp1-Directed blaOXA-181 Insertion in the mgrB Gene in the …

Á Sonnevend, A Ghazawi, R Hashmey… - Antimicrobial agents …, 2017 - Am Soc Microbiol
The emergence of pan-resistant Klebsiella pneumoniae strains is an increasing concern. In
the present study, we describe a cluster of 9 pan-resistant K. pneumoniae sequence type …

Emergence and Evolution of Multidrug-Resistant Klebsiella pneumoniae with both blaKPC and blaCTX-M Integrated in the Chromosome

W Huang, G Wang, R Sebra, J Zhuge… - Antimicrobial Agents …, 2017 - Am Soc Microbiol
The extended-spectrum-β-lactamase (ESBL)-and Klebsiella pneumoniae carbapenemase
(KPC)-producing Enterobacteriaceae represent serious and urgent threats to public health …

Discovery of mcr-1-Mediated Colistin Resistance in a Highly Virulent Escherichia coli Lineage

BM Forde, HM Zowawi, PNA Harris, L Roberts… - Msphere, 2018 - Am Soc Microbiol
Resistance to last-line polymyxins mediated by the plasmid-borne mobile colistin resistance
gene (mcr-1) represents a new threat to global human health. Here we present the complete …

Polymyxin Combinations Combat Escherichia coli Harboring mcr-1 and blaNDM-5: Preparation for a Postantibiotic Era

ZP Bulman, L Chen, TJ Walsh, MJ Satlin, Y Qian… - MBio, 2017 - Am Soc Microbiol
The rapid increase of carbapenem resistance in Gram-negative bacteria has resurrected the
importance of the polymyxin antibiotics. The recent discovery of plasmid-mediated …

Characterization of extensively drug-resistant or pandrug-resistant sequence type 147 and 101 OXA-48-producing Klebsiella pneumoniae causing bloodstream …

K Avgoulea, V Di Pilato, O Zarkotou… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Carbapenem-resistant Klebsiella pneumoniae causes important health care-associated
infections worldwide. An outbreak of sequence type 11 (ST11) OXA-48-producing K …