[HTML][HTML] Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges
MDA Paskeh, F Ghadyani, M Hashemi… - Pharmacological …, 2023 - Elsevier
Cancer progression results from activation of various signaling networks. Among these,
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of apoptosis …
The Role of Type 2 Diabetes Mellitus–Related Risk Factors and Drugs in Hepatocellular Carcinoma
Y Mai, L Meng, G Deng, Y Qin - Journal of Hepatocellular …, 2024 - Taylor & Francis
With changes in modern lifestyles, type 2 diabetes mellitus (T2DM) has become a global
epidemic metabolic disease, and hepatocellular carcinoma (HCC) is one of the leading …
epidemic metabolic disease, and hepatocellular carcinoma (HCC) is one of the leading …
Immunotherapy or targeted therapy as the first-line strategies for unresectable hepatocellular carcinoma: a network meta-analysis and cost-effectiveness analysis
K Liu, Y Zhu, H Zhu - Frontiers in Immunology, 2023 - frontiersin.org
Introduction The existence of many phase III randomized controlled trials (RCTs) of first-line
treatment for unresectable hepatocellular carcinoma (HCC) puzzle doctors and patients in …
treatment for unresectable hepatocellular carcinoma (HCC) puzzle doctors and patients in …
Oxoglutarate dehydrogenase-like inhibits the progression of hepatocellular carcinoma by inducing DNA damage through non-canonical function
X Jiang, J Peng, Y Xie, Y Xu, Q Liu, C Cheng… - Cell Death & …, 2023 - nature.com
Oxoglutarate dehydrogenase-like (OGDHL) is considered to be the isoenzyme of
oxyglutarate dehydrogenase (OGDH) in the OGDH complex, which degrades glucose and …
oxyglutarate dehydrogenase (OGDH) in the OGDH complex, which degrades glucose and …
[PDF][PDF] Risk factors for the development of hepatocellular carcinoma in Chengdu: a prospective cohort study.
OBJECTIVE: To investigate the incidence of hepatocellular carcinoma (HCC) in Chengdu,
identify the risk factors for the development of HCC in Chengdu and provide a reference for …
identify the risk factors for the development of HCC in Chengdu and provide a reference for …
Phellinus linteus activates Treg cells via FAK to promote M2 macrophage polarization in hepatocellular carcinoma
F Chen, M Gong, D Weng, Z Jin, G Han, Z Yang… - Cancer Immunology …, 2024 - Springer
Hepatocellular carcinoma (HCC) is the most prevalent malignant tumor worldwide. Within
HCC's tumor microenvironment, focal adhesion kinase (FAK) plays a critical role. Regulatory …
HCC's tumor microenvironment, focal adhesion kinase (FAK) plays a critical role. Regulatory …
Integrative analysis of disulfidptosis and immune microenvironment in hepatocellular carcinoma: a putative model and immunotherapeutic strategies
T Yang, J Liu, F Liu, J Lei, S Chen, Z Ma, P Ke… - Frontiers in …, 2024 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a malignant tumor with a high rate of
recurrence and m metastasis that does not respond well to current therapies and has a very …
recurrence and m metastasis that does not respond well to current therapies and has a very …
Trends of hepatocellular carcinoma (HCC) inpatients mortality and financial burden from 2011 to 2017: A nationwide analysis
A Wakil, YC Wu, N Mazzaferro… - Journal of Clinical …, 2024 - journals.lww.com
Method: This is a retrospective analysis utilizing the National Inpatient Sample (NIS)
database. All subjects admitted between 2011 and 2017 with a diagnosis of HCC were …
database. All subjects admitted between 2011 and 2017 with a diagnosis of HCC were …
Clinical outcomes associated with monotherapy and combination therapy of immune checkpoint inhibitors as first-line treatment for advanced hepatocellular …
Simple Summary Hepatocellular carcinoma (HCC) is one of the most malignant tumors.
Immune checkpoint inhibitors (ICIs)-based therapy has recently been demonstrated to …
Immune checkpoint inhibitors (ICIs)-based therapy has recently been demonstrated to …
Unveiling the flames: macrophage pyroptosis and its crucial role in liver diseases
L Ni, D Chen, Y Zhao, R Ye, P Fang - Frontiers in Immunology, 2024 - frontiersin.org
Macrophages play a critical role in innate immunity, with approximately 90% of the total
macrophage population in the human body residing in the liver. This population …
macrophage population in the human body residing in the liver. This population …