Quality control in mass spectrometry‐based proteomics

W Bittremieux, DL Tabb, F Impens… - Mass Spectrometry …, 2018 - Wiley Online Library
Mass spectrometry is a highly complex analytical technique and mass spectrometry‐based
proteomics experiments can be subject to a large variability, which forms an obstacle to …

Advances in the clinical use of metaproteomics

M Wolf, K Schallert, L Knipper, A Sickmann… - Expert review of …, 2023 - Taylor & Francis
Introduction Investigating the taxonomic and functional composition of human microbiomes
can aid in the understanding of disease etiologies, diagnosis, and therapy monitoring for …

The time has come for quantitative protein mass spectrometry tests that target unmet clinical needs

NPM Smit, LR Ruhaak, FP Romijn… - Journal of the …, 2021 - ACS Publications
Protein mass spectrometry (MS) is an enabling technology that is ideally suited for precision
diagnostics. In contrast to immunoassays with indirect readouts, MS quantifications are …

Mass spectrometry based proteomics as foodomics tool in research and assurance of food quality and safety

U Andjelković, D Josić - Trends in Food Science & Technology, 2018 - Elsevier
Background As a comprehensive discipline that studies food and nutrition, foodomics
requires reliable qualitative and quantitative information about the food proteome …

Clinical translation of MS-based, quantitative plasma proteomics: status, challenges, requirements, and potential

AJ Percy, S Byrns, SR Pennington… - Expert review of …, 2016 - Taylor & Francis
Introduction: Aided by the advent of advanced mass spectrometry (MS)-based technologies
and methodologies, quantitative proteomics has emerged as a viable technique to capture …

Mass spectrometry provides a highly sensitive noninvasive means of sequencing and tracking M-protein in the blood of multiple myeloma patients

Z McDonald, P Taylor, M Liyasova… - Journal of Proteome …, 2021 - ACS Publications
The amino acid sequence of the M-protein for multiple myeloma is unique compared to the
polyclonal antibodies in patients' blood. This uniqueness is exploited to develop an …

Clinical applications of MS‐based protein quantification

B Sabbagh, S Mindt, M Neumaier… - PROTEOMICS …, 2016 - Wiley Online Library
Mass spectrometry‐based assays are increasingly important in clinical laboratory medicine
and nowadays are already commonly used in several areas of routine diagnostics. These …

Use of recombinant proteins as a simple and robust normalization method for untargeted proteomics screening: exhaustive performance assessment

SI Anjo, I Simões, P Castanheira, M Grãos, B Manadas - Talanta, 2019 - Elsevier
The label-free quantitative mass spectrometry methods, in particular, the SWATH-MS
approach, have gained popularity and became a powerful technique for comparison of large …

Use of monolithic supports for high‐throughput protein and peptide separation in proteomics

U Andjelković, S Tufegdžić, M Popović - Electrophoresis, 2017 - Wiley Online Library
The exclusive properties of monolithic supports enable fast mass transfer, high porosity, low
back pressure, easy preparation process and miniaturisation, and the availability of different …

A standardized kit for automated quantitative assessment of candidate protein biomarkers in human plasma

AJ Percy, Y Mohammed, J Yang, CH Borchers - Bioanalysis, 2015 - Taylor & Francis
Background: An increasingly popular mass spectrometry-based quantitative approach for
health-related research in the biomedical field involves the use of stable isotope-labeled …