The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

Simple Summary The present review highlights and examines the importance of animal
models in relevant topics concerning current human and animal health. Over the past five …

Microplastics are plastic fragments of particle sizes less than 5 mm, which are widely
distributed in marine and terrestrial environments. In this study, earthworms Eisenia fetida …

The comet assay is a widely used test for the detection of DNA damage and repair activity.
However, there are interlaboratory differences in reported levels of baseline and induced …

The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It
can also be applied to cells isolated from treated animals. In this review, we highlight …

Large plastic litters degrade in the environment to micro-and nanoplastics, which may then
enter the food chain and lead to human exposure by ingestion. The present study explored …

Heavy metals pollution of soil and widespread application of neonicotinoid insecticides have
caused environmental problems worldwide. To evaluate ecological toxicity resulting from the …

The lethality and chemotherapy resistance of pancreatic cancer necessitates the urgent
development of innovative strategies to improve patient outcomes. To address this issue, we …

This review discusses several research studies that employed comet assay to evaluate the
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …

Highlights•Twelve different enzyme have been used in combination with the comet
assay.•The enzyme-modified comet assay detects several DNA lesions.•Fpg, followed by …