Lactose malabsorption and intolerance: pathogenesis, diagnosis and treatment

B Misselwitz, D Pohl, H Frühauf… - United European …, 2013 - journals.sagepub.com
Lactose malabsorption is a common condition caused by reduced expression or activity of
lactase in the small intestine. In such patients, lactose intolerance is characterized by …

Lactose intolerance: diagnosis, genetic, and clinical factors

R Mattar, DF de Campos Mazo… - Clinical and experimental …, 2012 - Taylor & Francis
Most people are born with the ability to digest lactose, the major carbohydrate in milk and
the main source of nutrition until weaning. Approximately 75% of the world's population …

Lactose digestion and the evolutionary genetics of lactase persistence

CJE Ingram, CA Mulcare, Y Itan, MG Thomas… - Human genetics, 2009 - Springer
It has been known for some 40 years that lactase production persists into adult life in some
people but not in others. However, the mechanism and evolutionary significance of this …

Lactose intolerance and bone health: the challenge of ensuring adequate calcium intake

JK Hodges, S Cao, DP Cladis, CM Weaver - Nutrients, 2019 - mdpi.com
Calcium is an important nutrient with impact upon many biological systems, most notably
bone. Ensuring adequate calcium intake throughout the lifespan is essential to building and …

Genome-wide scans for footprints of natural selection

TK Oleksyk, MW Smith… - … Transactions of the …, 2010 - royalsocietypublishing.org
Detecting recent selected 'genomic footprints' applies directly to the discovery of disease
genes and in the imputation of the formative events that molded modern population genetic …

Effects of resistance and aerobic exercise on physical function, bone mineral density, OPG and RANKL in older women

EA Marques, F Wanderley, L Machado, F Sousa… - Experimental …, 2011 - Elsevier
This study compared the effects of a resistance training protocol and a moderate-impact
aerobic training protocol on bone mineral density (BMD), physical ability, serum …

[HTML][HTML] Lactose intolerance and health.

TJ Wilt, A Shaukat, T Shamliyan, BC Taylor… - Evidence report …, 2010 - europepmc.org
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Multicomponent training program with weight-bearing exercises elicits favorable bone density, muscle strength, and balance adaptations in older women

EA Marques, J Mota, L Machado, F Sousa… - Calcified tissue …, 2011 - Springer
Physical exercise is advised as a preventive and therapeutic strategy against aging-induced
bone weakness. In this study we examined the effects of 8-month multicomponent training …

Molecular genetics of human lactase deficiencies

I Järvelä, S Torniainen, KL Kolho - Annals of medicine, 2009 - Taylor & Francis
Lactase non-persistence (adult-type hypolactasia) is present in more than half of the human
population and is caused by the down-regulation of lactase enzyme activity during …

Lactase persistence, milk intake, hip fracture and bone mineral density: a study of 97 811 Danish individuals and a meta‐analysis

HKM Bergholdt, MK Larsen, A Varbo… - Journal of internal …, 2018 - Wiley Online Library
Background Whether a causal relationship exists between milk intake and reduced risk of
fractures is unclear. Objectives We tested the hypothesis that genetically determined milk …