Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN) are a heterogeneous
subgroup of rare neoplasms that represent about a third of all poorly differentiated …

Carcinoma of unknown primary origin (CUP) is one of the 10 most prevalent malignancies.
CUP patients in whom a site of origin can be ascribed have better outcomes than those in …

To date, empirical literature has generally been considered lacking in relation to
neuroendocrine carcinomas (NECs), the highly malignant subgroup of neuroendocrine …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are classified based on
morphology and graded based on their proliferation rate as either well-differentiated low …

Simple Summary Patients with cancer of unknown primary site suffer the burden of an
uncertain disease, which is characterized by the impossibility to identify the tissue where the …

Background The 2010 World Health Organization (WHO) classification of
gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) introduced morphology …

Importance Gastric neuroendocrine carcinoma and mixed adenoneuroendocrine carcinoma
are rare pathological types of gastric cancer, and there is a lack of multicenter studies …

Objective High-grade neuroendocrine carcinoma of uterine cervix (HGNCUC) has been
recognized as a highly malignant tumor. Therapeutic strategy specific to neuroendocrine …

Opinion statement In the 2019 WHO guidelines, the classification of gastro-entero-
pancreatic neuroendocrine neoplasms (GEP NEN) has changed from one being based on …