Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Atherosclerosis, the formation of fibrofatty lesions in the artery wall, causes much morbidity
and mortality worldwide, including most myocardial infarctions and many strokes, as well as …

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …

Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at
sites of blood flow disturbance. The disease usually remains silent until a breakdown of …

For several decades, the role of hormone-replacement therapy (HRT) has been debated.
Early observational data on HRT showed many benefits, including a reduction in coronary …

Background: The development of thoracic aortic dissection (TAD) is closely related to
extracellular matrix degradation and vascular smooth muscle cell (VSMC) transformation …

Atherosclerosis is an inflammatory disease within the arterial wall that is responsible for
several important adverse vascular events, including coronary artery disease, myocardial …

The notion that heart attacks develop from coronary-artery stenosis is an oversimplification
of a process involving lipid metabolism, inflammation, macrophage activation, collagen …

Experimental work has elucidated molecular and cellular pathways of inflammation that
promote atherosclerosis. Unraveling the roles of cytokines as inflammatory messengers …