Stress and the dopaminergic reward system

JH Baik - Experimental & molecular medicine, 2020 - nature.com
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …

The changing opioid crisis: development, challenges and opportunities

ND Volkow, C Blanco - Molecular psychiatry, 2021 - nature.com
The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …

The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis

MD Scofield, JA Heinsbroek, CD Gipson… - Pharmacological …, 2016 - ASPET
The nucleus accumbens is a major input structure of the basal ganglia and integrates
information from cortical and limbic structures to mediate goal-directed behaviors. Chronic …

Natural neural projection dynamics underlying social behavior

LA Gunaydin, L Grosenick, JC Finkelstein, IV Kauvar… - Cell, 2014 - cell.com
Social interaction is a complex behavior essential for many species and is impaired in major
neuropsychiatric disorders. Pharmacological studies have implicated certain …

Interface engineering of highly efficient perovskite solar cells

H Zhou, Q Chen, G Li, S Luo, T Song, HS Duan… - Science, 2014 - science.org
Advancing perovskite solar cell technologies toward their theoretical power conversion
efficiency (PCE) requires delicate control over the carrier dynamics throughout the entire …

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

G Dölen, A Darvishzadeh, KW Huang, RC Malenka - Nature, 2013 - nature.com
Social behaviours in species as diverse as honey bees and humans promote group survival
but often come at some cost to the individual. Although reinforcement of adaptive social …

The ins and outs of the striatum: role in drug addiction

LM Yager, AF Garcia, AM Wunsch, SM Ferguson - Neuroscience, 2015 - Elsevier
Addiction is a chronic relapsing disorder characterized by the loss of control over drug
intake, high motivation to obtain the drug, and a persistent craving for the drug …

Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections

YM Kupchik, RM Brown, JA Heinsbroek, MK Lobo… - Nature …, 2015 - nature.com
It is widely accepted that D1 dopamine receptor–expressing striatal neurons convey their
information directly to the output nuclei of the basal ganglia, whereas D2-expressing …

Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models

P Mews, AM Cunningham, J Scarpa… - Science …, 2023 - science.org
Cocaine use disorder (CUD) is an intractable syndrome, and rising overdose death rates
represent a substantial public health crisis that exacts tremendous personal and financial …

Dopamine signaling in reward-related behaviors

JH Baik - Frontiers in neural circuits, 2013 - frontiersin.org
Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA mesolimbic neurotransmission have been found to …