Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …

Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …

Iron dysregulation has been implicated in multiple neurodegenerative diseases, including
Parkinson's disease (PD). Iron-loaded microglia are frequently found in affected brain …

Genetic studies of Alzheimer disease (AD) have prioritized variants in genes related to the
amyloid cascade, lipid metabolism, and neuroimmune modulation. However, the cell …

Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …

Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …

Ferroptosis is an iron-and lipid peroxidation (LPO)-mediated programmed cell death type.
Recently, mounting evidence has indicated the involvement of ferroptosis in …

Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …

Ferroptosis is defined as an iron-dependent regulated form of cell death driven by lipid
peroxidation. In the past decade, it has been implicated in the pathogenesis of various …