Presynaptic calcium channels: specialized control of synaptic neurotransmitter release
AC Dolphin, A Lee - Nature Reviews Neuroscience, 2020 - nature.com
Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …
specialized for the conversion of electrical impulses into the exocytotic release of …
Targeting voltage-gated calcium channels in neurological and psychiatric diseases
GW Zamponi - Nature reviews Drug discovery, 2016 - nature.com
Voltage-gated calcium channels are important regulators of brain, heart and muscle
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …
functions, and their dysfunction can give rise to pathophysiological conditions ranging from …
Auditory synaptopathy, auditory neuropathy, and cochlear implantation
AE Shearer, MR Hansen - Laryngoscope investigative …, 2019 - Wiley Online Library
Cochlear implantation has become the standard‐of‐care for adults and children with severe
to profound hearing loss. There is growing evidence that qualitative as well as quantitative …
to profound hearing loss. There is growing evidence that qualitative as well as quantitative …
[HTML][HTML] Auditory neuropathy spectrum disorders: from diagnosis to treatment: literature review and case reports
RD De Siati, F Rosenzweig, G Gersdorff… - Journal of clinical …, 2020 - mdpi.com
Auditory neuropathy spectrum disorder (ANSD) refers to a range of hearing impairments
characterized by deteriorated speech perception, despite relatively preserved pure-tone …
characterized by deteriorated speech perception, despite relatively preserved pure-tone …
Diversity matters—extending sound intensity coding by inner hair cells via heterogeneous synapses
Our sense of hearing enables the processing of stimuli that differ in sound pressure by more
than six orders of magnitude. How to process a wide range of stimulus intensities with …
than six orders of magnitude. How to process a wide range of stimulus intensities with …
Voltage-gated calcium channels: key players in sensory coding in the retina and the inner ear
T Pangrsic, JH Singer, A Koschak - Physiological reviews, 2018 - journals.physiology.org
Calcium influx through voltage-gated Ca (CaV) channels is the first step in synaptic
transmission. This review concerns CaV channels at ribbon synapses in primary sense …
transmission. This review concerns CaV channels at ribbon synapses in primary sense …
Hair cells use active zones with different voltage dependence of Ca2+ influx to decompose sounds into complementary neural codes
TL Ohn, MA Rutherford, Z Jing, S Jung… - Proceedings of the …, 2016 - National Acad Sciences
For sounds of a given frequency, spiral ganglion neurons (SGNs) with different thresholds
and dynamic ranges collectively encode the wide range of audible sound pressures …
and dynamic ranges collectively encode the wide range of audible sound pressures …
Calcium sensors in neuronal function and dysfunction
RD Burgoyne, N Helassa… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Calcium signaling in neurons as in other cell types can lead to varied changes in cellular
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …
function. Neuronal Ca2+ signaling processes have also become adapted to modulate the …
Review of hair cell synapse defects in sensorineural hearing impairment
Review of Hair Cell Synapse Defects in Sensorineural Hearing... : Otology & Neurotology
Review of Hair Cell Synapse Defects in Sensorineural Hearing Impairment : Otology & …
Review of Hair Cell Synapse Defects in Sensorineural Hearing Impairment : Otology & …