Mitochondrial signalling and homeostasis: from cell biology to neurological disease
JJ Collier, M Oláhová, TG McWilliams… - Trends in …, 2023 - cell.com
Efforts to understand how mitochondrial dysfunction contributes to neurodegeneration have
primarily focussed on the role of mitochondria in neuronal energy metabolism. However …
primarily focussed on the role of mitochondria in neuronal energy metabolism. However …
Mitochondrial fission mediated by Drp1-Fis1 pathway and neurodegenerative diseases
W Shi, C Tan, C Liu, D Chen - Reviews in the Neurosciences, 2023 - degruyter.com
In recent years, the role of mitochondrial dynamics in neurodegenerative diseases has
becoming increasingly important. More and more evidences have shown that in pathological …
becoming increasingly important. More and more evidences have shown that in pathological …
Image analysis of the mitochondrial network morphology with applications in cancer research
Mitochondria are dynamic organelles that integrate bioenergetics, biosynthesis, and
signaling in cells and regulate redox homeostasis, apoptotic pathways, and cell proliferation …
signaling in cells and regulate redox homeostasis, apoptotic pathways, and cell proliferation …
[HTML][HTML] Unlocking the mitochondria for nanomedicine-based Treatments: Overcoming biological Barriers, improving Designs, and selecting verification techniques
C Pegoraro, I Domingo, I Conejos-Sánchez… - Advanced Drug Delivery …, 2024 - Elsevier
Enhanced targeting approaches will support the treatment of diseases associated with
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …
dysfunctional mitochondria, which play critical roles in energy generation and cell survival …
AI-driven precision subcellular navigation with fluorescent probes
Y Zhu, Y Fang, W Huang, W Zhang, F Chen… - Journal of Materials …, 2024 - pubs.rsc.org
Precise navigation within intricate biological systems is pivotal for comprehending cellular
functions and diagnosing diseases. Fluorescent molecular probes, designed to target …
functions and diagnosing diseases. Fluorescent molecular probes, designed to target …
Novel DNM1L variants impair mitochondrial dynamics through divergent mechanisms
Imbalances in mitochondrial and peroxisomal dynamics are associated with a spectrum of
human neurological disorders. Mitochondrial and peroxisomal fission both involve dynamin …
human neurological disorders. Mitochondrial and peroxisomal fission both involve dynamin …
Mitochondrial nanoprobe for precise cellular and drug analysis via graph Neural network
H He, G Qin, M Xue, Z Feng, J Mao, W Tao… - Chemical Engineering …, 2024 - Elsevier
Mitochondrial morphology is crucial for cell identification and drug toxicity evaluation, yet it is
challenged by mitochondrial complexities and limitations in imaging technologies. We …
challenged by mitochondrial complexities and limitations in imaging technologies. We …