Reactive oxygen species (ROS) have been described to induce a broad range of redox-
dependent signaling reactions in physiological conditions. Nevertheless, an excessive …

Alzheimer's disease (AD) is the most common neurodegenerative disease illustrated by
neuronal dysfunctions, leading to memory weaknesses and personality changes mostly in …

Neurodegenerative diseases are characterized by gradually progressive, selective loss of
anatomically or physiologically related neuronal systems that produce brain damage from …

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease
characterized by the extracellular deposition of amyloid plaques. Investigation into the …

Environmental enrichment (EE) is an environmental paradigm encompassing sensory,
cognitive, and physical stimulation at a heightened level. Previous studies have reported the …

Neurodegenerative diseases (NDDs) are irreversible, progressive diseases with no effective
treatment. The hallmark of NDDs is the aggregation of misfolded, modified proteins, which …

Background A growing body of research shows that drug monomers from traditional
Chinese herbal medicines have antineuroinflammatory and neuroprotective effects that can …

Dysregulation of protein homeostasis, proteostasis, is a distinctive hallmark of many
neurodegenerative disorders and aging. Deleteriously, the accumulation of aberrant …

Psychiatric and neurodegenerative disorders are amongst the most prevalent and
debilitating diseases, but current treatments either have low success rates, greatly due to the …

Alzheimer's disease (AD), as a neurodegenerative disorder, usually develops slowly but
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …