This review discusses a set of instrumental and computational methods that are used to
characterize hydrated forms of APIs (active pharmaceutical ingredients). The focus has been …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

This study reports the development of ritonavir-copovidone amorphous solid dispersions
(ASDs) and dosage forms thereof using selective laser sintering (SLS) 3-dimensional (3-D) …

A significant majority of the 20 approved nanoformulations consist predominantly of
nanocrystals (NCs). NCs are nanosized drug moieties comprising 100% of the drug with …

Thermal processing has gained much interest in the pharmaceutical industry, particularly for
the enhancement of solubility, bioavailability, and dissolution of active pharmaceutical …

Solid dispersion (SD) system has been used as an effective formulation strategy to increase
in vitro and in vivo performances of poorly water-soluble drugs, such as …

Since the emergence of Soluplus®(SOL) as a commercial graft copolymer, several
publications have been issued on its promising potential as a solubilizing excipient that …

Additive manufacturing of pharmaceutical formulations offers advanced micro-structure
control of oral solid dose (OSD) forms targeting not only customised dosing of an active …

Hot melt extrusion (HME) is a technique applied in the preparation of pharmaceutical
amorphous solid dispersions (ASD). Notably it is important to prevent thermal degradation of …

The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a
poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions …