Potential applications of peptide nucleic acid in biomedical domain
Abstract Peptide Nucleic Acid (PNA) are DNA/RNA synthetic analogs with 2‐([2‐aminoethyl]
amino) acetic acid backbone. They partake unique antisense and antigene properties, just …
amino) acetic acid backbone. They partake unique antisense and antigene properties, just …
Recognition of target site in various forms of DNA and RNA by peptide nucleic acid (PNA): From fundamentals to practical applications
X Liang, M Liu, M Komiyama - Bulletin of the Chemical Society of …, 2021 - academic.oup.com
Peptide nucleic acid (PNA) is a DNA analog, in which the sugar-phosphate backbone in
DNA is replaced by poly [N-(2-aminoethyl) glycine]. Since its discovery in the early 1990s …
DNA is replaced by poly [N-(2-aminoethyl) glycine]. Since its discovery in the early 1990s …
A Biotinylated cpFIT-PNA Platform for the Facile Detection of Drug Resistance to Artemisinin in Plasmodium falciparum
O Tepper, DH Appella, H Zheng, R Dzikowski… - ACS …, 2024 - ACS Publications
The evolution of drug resistance to many antimalarial drugs in the lethal strain of malaria
(Plasmodium falciparum) has been a great concern over the past 50 years. Among these …
(Plasmodium falciparum) has been a great concern over the past 50 years. Among these …
[HTML][HTML] Peptide-based optical biosensors: a promising approach for early-stage cancer detection
GK Soni, P Manhas, RK Sharma - Biosensors and Bioelectronics: X, 2022 - Elsevier
Cancer is the leading cause of 10 million deaths worldwide in 2020, which is exponentially
increasing per year. The early detection and effective treatment of cancer can save millions …
increasing per year. The early detection and effective treatment of cancer can save millions …
Caffeic acid phenethyl ester surmounts acquired resistance of AZD9291 in non‐small cell lung cancer cells
Y Twum, K Marshall, W Gao - BioFactors, 2023 - Wiley Online Library
Epithelial growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) are the first‐line
therapy for EGFR mutated non‐small cell lung cancer (NSCLC); however, resistance rapidly …
therapy for EGFR mutated non‐small cell lung cancer (NSCLC); however, resistance rapidly …
Analysis of single nucleotide-mutated single-cancer cells using the combined technologies of single-cell microarray chips and peptide nucleic acid-DNA probes
Research into cancer cells that harbor gene mutations relating to anticancer drug-resistance
at the single-cell level has focused on the diagnosis of, or treatment for, cancer. Several …
at the single-cell level has focused on the diagnosis of, or treatment for, cancer. Several …
FRET probe for detecting two mutations in one EGFR mRNA
Technologies for visualizing and tracking RNA are essential in molecular biology, including
in disease-related fields. In this study, we propose a novel probe set (DAt-probe and T …
in disease-related fields. In this study, we propose a novel probe set (DAt-probe and T …
Localization of EGFR mutations in non-small-cell lung cancer tissues using mutation-specific PNA-DNA probes
H Shigeto, H Miyata, T Ashizawa… - Cancer Genomics & …, 2023 - cgp.iiarjournals.org
Abstract Background/Aim: Epidermal growth factor receptor (EGFR) signaling inhibitors are
potent therapeutic agents for EGFR-mutant non-small-cell lung cancer, but the effects of …
potent therapeutic agents for EGFR-mutant non-small-cell lung cancer, but the effects of …
Explorations into peptide nucleic acid contrast agents as emerging scaffolds for breakthrough solutions in medical imaging and diagnosis
Peptide nucleic acids (PNAs, nucleic acid analogues with a peptide backbone rather than a
phosphoribosyl backbone) have emerged as promising chemical agents in antigene or …
phosphoribosyl backbone) have emerged as promising chemical agents in antigene or …
Selective cell retrieval method using light-responsive gas-generating polymer-based microarrays
Selective cell retrieval from base material is necessary for developing and improving cell
analyzing technologies as well as regenerative medicine. Many conventional technologies …
analyzing technologies as well as regenerative medicine. Many conventional technologies …