Non-typhoidal Salmonella represents an important human and animal pathogen world-wide.
Most human salmonellosis cases are foodborne, but each year infections are also acquired …

Whether it is in the setting of disease or in a healthy state, the human body contains a
diverse range of microorganisms, including bacteria and fungi. The interactions between …

The biguanide drug metformin is widely prescribed to treat type 2 diabetes and metabolic
syndrome, but its mode of action remains uncertain. Metformin also increases lifespan in …

Abstract Background The nematode Caenorhabditis elegans is a major model organism in
laboratory biology. Very little is known, however, about its ecology, including where it …

The term innate immunity refers to a number of evolutionary ancient mechanisms that serve
to defend animals and plants against infection. Genetically tractable model organisms …

The human opportunistic pathogen Serratia marcescens is a bacterium with a broad host
range, and represents a growing problem for public health. Serratia marcescens kills …

The microbiological safety of fresh produce is monitored almost exclusively by culture-based
detection methods. However, bacterial food-borne pathogens are known to enter a viable …

The implementation of infection models that approximate human disease is essential for
understanding pathogenesis at the molecular level and for testing new therapies before they …

Genetic analysis of host–pathogen interactions has been hampered by the lack of
genetically tractable models of such interactions. We showed previously that the human …

We found that the well-studied nematode Caenorhabditis elegans can use various yeasts,
including Cryptococcus laurentii and Cryptococcus kuetzingii, as a sole source of food …