Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Bone is consisted of bone matrix, cells and bioactive factors, and bone matrix is the
combination of inorganic minerals and organic polymers. Type I collagen fibril made of five …

Our populations are aging. Some experts predict that 30% of hospital beds will soon be
occupied by osteoporosis patients. Statistics show that 20% of patients suffering from an …

Bone, as a mineralized composite of inorganic (mostly carbonated hydroxyapatite) and
organic (mainly type I collagen) phases, possesses a unique combination of remarkable …

Abstract The role of Bone Tissue Engineering in the field of Regenerative Medicine has
been the topic of substantial research over the past two decades. Technological advances …

Additive manufacturing, also known as 3D printing, has emerged over the past 3 decades as
a disruptive technology for rapid prototyping and manufacturing. Vat polymerization, powder …

A systematic analysis of results available from in vitro, in vivo and clinical trials on the effects
of biocompatible calcium phosphate (CaP) coatings is presented. An overview of the most …

The discovery of osteoinductivity of calcium phosphate (Ca-P) ceramics has set an enduring
paradigm of conferring biological regenerative activity to materials with carefully designed …

Strategies for bone tissue regeneration have been continuously evolving for the last 25
years since the introduction of the “tissue engineering” concept. The convergence of the life …

Bone defects resulting from trauma, illness or congenital abnormalities represent a
significant challenge to global health. Conventional treatments such as autographs and …