Breast cancer is the most common form of cancer diagnosed in women worldwide and the
second leading cause of cancer-related deaths in the USA. Despite the development of …

Abstract Background Cancer stem cells (CSCs) or tumor-initiating cells (TICs) represent a
small population of cancer cells with self-renewal and tumor-initiating properties. Unlike the …

Introduction: Ten years ago, we put forward the metabolo-oncogenic nature of fatty acid
synthase (FASN) in breast cancer. Since the conception of this hypothesis, which provided a …

Globally, breast cancer is the most frequently diagnosed cancer among women. The major
unresolved problems with metastatic breast cancer is recurrence after receiving objective …

Cancer heterogeneity constitutes the major source of disease progression and therapy
failure. Tumors comprise functionally diverse subpopulations, with cancer stem cells (CSCs) …

Background Resistance to cell death, a protective mechanism for removing damaged cells,
is a “Hallmark of Cancer” that is essential for cancer progression. Increasing attention to …

Increasing evidence highlights the role of lipid metabolism in tumorigenesis and tumor
progression. Targeting the processes of lipid metabolism, including lipogenesis, lipid …

Emerging evidence in cancer metabolomics has identified reprogrammed metabolic
pathways to be a major hallmark of cancer, among which deregulated lipid metabolism is a …

The incidence of kidney cancer has been increasing globally during the past two decades.
Renal cell carcinoma (RCC) is the most aggressive subtype of kidney cancer, which usually …

When fighting cancer, knowledge on metabolism has always been important. Today, it
matters more than ever. The restricted cataloging of cancer genomes is quite unlikely to …