Poor water-solubility remains a typical property of drug candidates in pharmaceutical
development pipelines today. Various processes have been developed to increase the …

With the FDA approval of the first 3D printed tablet, Spritam®, there is now precedence set
for the utilization of 3D printing for the preparation of drug delivery systems. The capabilities …

Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

INTRODUCTION The gut microbiota is implicated in the metabolism of many medical drugs,
with consequences for interpersonal variation in drug efficacy and toxicity. However …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

There have been major advances in the development of edible colloidal delivery systems for
hydrophobic bioactives in recent years. However, there are still many challenges associated …

Polyphenols are natural organic compounds produced by plants, acting as antioxidants by
reacting with ROS. These compounds are widely consumed in daily diet and many studies …

The current phase of drug development is witnessing an oncoming crisis due to the
combined effects of increasing R&D costs, decreasing number of new drug molecules being …

This book covers the formation, properties, characterization, and application of different
kinds of colloidal delivery systems that can be utilized within the food industry, including …

Solubility optimization is a crucial step to obtaining oral PROTACs. Here we measured the
thermodynamic solubilities (log S) of 21 commercial PROTACs. Next, we measured BRlogD …