Injured brains and adaptive networks: the benefits and costs of hyperconnectivity

FG Hillary, JH Grafman - Trends in cognitive sciences, 2017 - cell.com
A common finding in human functional brain-imaging studies is that damage to neural
systems paradoxically results in enhanced functional connectivity between network regions …

[HTML][HTML] Network collapse and cognitive impairment in multiple sclerosis

MM Schoonheim, KA Meijer, JJG Geurts - Frontiers in neurology, 2015 - frontiersin.org
The current field of multiple sclerosis (MS) research is an active and highly interesting one:
structural abnormalities such as inflammatory lesions and brain atrophy are studied with a …

Delayed cortical development in fetuses with complex congenital heart disease

C Clouchoux, AJ Du Plessis, M Bouyssi-Kobar… - Cerebral …, 2013 - academic.oup.com
Neurologic impairment is a major complication of complex congenital heart disease (CHD).
A growing body of evidence suggests that neurologic dysfunction may be present in a …

Hyperconnectivity is a fundamental response to neurological disruption.

FG Hillary, CA Roman, U Venkatesan… - …, 2015 - psycnet.apa.org
Objective: In the cognitive and clinical neurosciences, the past decade has been marked by
dramatic growth in a literature examining brain “connectivity” using noninvasive methods …

Sodium accumulation is associated with disability and a progressive course in multiple sclerosis

D Paling, BS Solanky, F Riemer, DJ Tozer… - Brain, 2013 - academic.oup.com
Neuroaxonal loss is a major substrate of irreversible disability in multiple sclerosis, however,
its cause is not understood. In multiple sclerosis there may be intracellular sodium …

[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: from regions to systems and time-varying analysis. Current status and future perspective

MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …

[HTML][HTML] Cognitive rehabilitation in multiple sclerosis: the role of plasticity

ND Chiaravalloti, HM Genova, J DeLuca - Frontiers in neurology, 2015 - frontiersin.org
Cognitive deficits are common in multiple sclerosis (MS), documented at many stages of the
disease. Both structural and functional neuroimaging have demonstrated a relationship with …

Pathology and MRI: exploring cognitive impairment in MS

F Paul - Acta Neurologica Scandinavica, 2016 - Wiley Online Library
Cognitive impairment is a frequent symptom in people with multiple sclerosis, affecting up to
70% of patients. This article reviews the published association of cognitive dysfunction with …

Symptom interconnectivity in multiple sclerosis: a narrative review of potential underlying biological disease processes

T Chitnis, J Vandercappellen, M King… - Neurology and Therapy, 2022 - Springer
Introduction Fatigue, cognitive impairment, depression, and pain are highly prevalent
symptoms in multiple sclerosis (MS). These often co-occur and may be explained by a …

Symptomatic treatment and management of multiple sclerosis

A Toosy, O Ciccarelli, A Thompson - Handbook of clinical neurology, 2014 - Elsevier
The range of symptoms which occur in multiple sclerosis (MS) can have disabling functional
consequences for patients and lead to significant reductions in their quality of life. MS …