Impact of frailty on outcomes in surgical patients: a systematic review and meta-analysis
Importance Age has historically been used to predict negative post-surgical outcomes. The
concept of frailty was introduced to explain the discrepancies that exist between patients' …
concept of frailty was introduced to explain the discrepancies that exist between patients' …
Peri‐operative optimisation of elderly and frail patients: a narrative review
SP Chan, KY Ip, MG Irwin - Anaesthesia, 2019 - Wiley Online Library
With increasing life expectancy and technological advancement, provision of anaesthesia
for elderly patients has become a significant part of the overall case‐load. These patients …
for elderly patients has become a significant part of the overall case‐load. These patients …
The 5-factor modified frailty index: an effective predictor of mortality in brain tumor patients
OBJECTIVE Health measures such as the Charlson Comorbidity Index (CCI) and the 11-
factor modified frailty index (mFI-11) have been employed to predict general medical and …
factor modified frailty index (mFI-11) have been employed to predict general medical and …
The burden of frailty among US veterans and its association with mortality, 2002–2012
AR Orkaby, L Nussbaum, YL Ho… - The Journals of …, 2019 - academic.oup.com
Background Frailty is a key determinant of clinical outcomes. We sought to describe frailty
among US Veterans and its association with mortality. Methods Nationwide retrospective …
among US Veterans and its association with mortality. Methods Nationwide retrospective …
Association of frailty with short-term outcomes, organ support and resource use in critically ill patients
FG Zampieri, TJ Iwashyna, EM Viglianti… - Intensive care …, 2018 - Springer
Purpose Frail patients are known to experience poor outcomes. Nevertheless, we know less
about how frailty manifests itself in patients' physiology during critical illness and how it …
about how frailty manifests itself in patients' physiology during critical illness and how it …
Frailty-aware care: giving value to frailty assessment across different healthcare settings
Healthcare systems need to adapt to better serve an aging population with complex
presentations. Frailty assessments are a potential means to address this heterogeneity in …
presentations. Frailty assessments are a potential means to address this heterogeneity in …
Geriatric physiology and the frailty syndrome
KT Khan, K Hemati… - Anesthesiology …, 2019 - anesthesiology.theclinics.com
The prevalence of older adults undergoing surgery is expected to increase as the population
ages. 1 Because of physiologic decline and loss of functional reserve, older patients are at a …
ages. 1 Because of physiologic decline and loss of functional reserve, older patients are at a …
Routine frailty assessment predicts postoperative complications in elderly patients across surgical disciplines–a retrospective observational study
O Birkelbach, R Mörgeli, C Spies, M Olbert, B Weiss… - BMC …, 2019 - Springer
Background Frailty is a frequent and underdiagnosed functional syndrome involving
reduced physiological reserves and an increased vulnerability against stressors, with severe …
reduced physiological reserves and an increased vulnerability against stressors, with severe …
Systematic review and meta-analysis of frailty as a predictor of morbidity and mortality after major abdominal surgery
Background Frailty is associated with poor prognosis, but the multitude of definitions and
scales of assessment makes the impact on outcomes difficult to assess. The aim of this study …
scales of assessment makes the impact on outcomes difficult to assess. The aim of this study …
Impact of hospital volume on outcomes following head and neck cancer surgery and flap reconstruction
Objective/Hypothesis Utilization of flaps for reconstruction of large head and neck cancer
(HNCA) defects has become more prevalent. The present study aimed to assess the impact …
(HNCA) defects has become more prevalent. The present study aimed to assess the impact …