[HTML][HTML] Inositols: from established knowledge to novel approaches

S Dinicola, V Unfer, F Facchinetti, CO Soulage… - International Journal of …, 2021 - mdpi.com
Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in
many biological pathways. Since the discovery of their involvement in endocrine signal …

[HTML][HTML] Oxidative stress and male fertility: role of antioxidants and inositols

MN De Luca, M Colone, R Gambioli, A Stringaro… - Antioxidants, 2021 - mdpi.com
Infertility is defined as a couple's inability to conceive after at least one year of regular
unprotected intercourse. This condition has become a global health problem affecting …

[HTML][HTML] Cryopreservation of gametes and embryos and their molecular changes

E Estudillo, A Jiménez, PE Bustamante-Nieves… - International journal of …, 2021 - mdpi.com
The process of freezing cells or tissues and depositing them in liquid nitrogen at–196° C is
called cryopreservation. Sub-zero temperature is not a physiological condition for cells and …

Superior effect of broccoli methanolic extract on control of oxidative damage of sperm cryopreservation and reproductive performance in rats: A comparison with …

M Raeeszadeh, B Shokrollahi, A Akbari - Theriogenology, 2022 - Elsevier
Sperm cryopreservation is one of the important reproductive biotechnology. However, during
the sperm cryopreservation, reactive oxygen species (ROS) are produced which disrupt the …

Breakthroughs in the use of inositols for assisted reproductive treatment (ART)

F Facchinetti, MSB Espinola, D Dewailly… - Trends in Endocrinology …, 2020 - cell.com
It is well known that myo-inositol (MI) and D-chiro-inositol (DCI) are insulin-sensitizing
agents, and MI is of proven utility in polycystic ovary syndrome (PCOS). In addition, MI plays …

[HTML][HTML] Redox balance in male infertility: Excellence through moderation—“Μέτρον ἄριστον”

EN Symeonidis, E Evgeni, V Palapelas, D Koumasi… - Antioxidants, 2021 - mdpi.com
Male infertility, a relatively common and multifactorial medical condition, affects
approximately 15% of couples globally. Based on WHO estimates, a staggering 190 million …

Endogenous and exogenous antioxidants as a tool to ameliorate male infertility induced by reactive oxygen species

T R. Dias, D Martin-Hidalgo, B M. Silva… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Antioxidants are essential for the maintenance of cellular redox
homeodynamics in the male reproductive tract, playing a key role in fertilizing potential …

[HTML][HTML] Human sperm as an in vitro model to assess the efficacy of antioxidant supplements during sperm handling: A narrative review

E Moretti, C Signorini, R Corsaro, M Giamalidi… - Antioxidants, 2023 - mdpi.com
Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due
to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction …

Myo‐inositol in health and disease: its impact on semen parameters and male fertility

MH Vazquez-Levin, GL Verón - Andrology, 2020 - Wiley Online Library
Abstract Background Myo‐inositol (cis‐1, 2, 3, 5‐trans‐4, 6‐cyclohexanehexol; MI) is the
most prominent of nine inositol stereoisomers. MI, its phosphate derivatives, and associated …

[HTML][HTML] Overview on the antioxidants, egg yolk alternatives, and mesenchymal stem cells and derivatives used in canine sperm cryopreservation

FY Mahiddine, MJ Kim - Animals, 2021 - mdpi.com
Simple Summary Canine sperm cryopreservation is a method commonly used in veterinary
clinics and laboratories. The present article reviews the antioxidants used in canine sperm …