Abnormal vasculature is one of the most conspicuous traits of tumor tissue, largely
contributing to tumor immune evasion. The deregulation mainly arises from the potentiated …

CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a
major global health and economic burden. Previously, we provided evidence that there is a …

Hanahan and Weinberg have proposed 10 organizing principles that enable growth and
metastatic dissemination of cancer cells. These distinctive and complementary capabilities …

Increasing evidence suggests that platelets play a predominant role in colon and breast
cancer metastasis, but the underlying molecular mechanisms remain elusive. Glycoprotein …

Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

The results of trials with sodium-glucose cotransporter 2 (SGLT2) inhibitors raised the
possibility that this class of drugs provides cardiovascular benefits independently from their …

Galectins are glycan-binding proteins with broad roles in physiological and pathological
processes. Here, Rabinovich and colleagues discuss the therapeutic relevance of galectins …

Background High probability of metastasis limited the long-term survival of patients with
hepatocellular carcinoma (HCC). Our previous study revealed that Galectin-3 was closely …

Galectins, a family of glycan-binding proteins, are well-known for their role in shaping the
immune microenvironment. They can directly affect the activity and survival of different …