Mitochondria are the source of cellular energy production and are present in different types
of cells. However, their function is especially important for the heart due to the high demands …

The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

Isoprenoid quinones are one of the most important groups of compounds occurring in
membranes of living organisms. These compounds are composed of a hydrophilic head …

The burden of cardiovascular and metabolic diseases is increasing with every year.
Although the management of these conditions has improved greatly over the years, it is still …

Cardiovascular diseases (CVDs) are serious public health issues and are responsible for
nearly one-third of global deaths. Mitochondrial dysfunction is accountable for the …

Quinones are a class of natural and synthetic compounds that have several beneficial
effects. Quinones are electron carriers playing a role in photosynthesis. As vitamins, they …

Previously, we demonstrated that ischemia induces mitochondrial damage and dysfunction
that persist throughout reperfusion and impact negatively on postischemic functional …

Statin therapy may lower plasma coenzyme Q10 (CoQ10) concentrations, but the evidence
as to the significance of this effect is unclear. We assessed the impact of statin therapy on …

Coenzyme Q10 (CoQ 10) is an effective natural antioxidant with a fundamental role in
cellular bioenergetics and numerous known health benefits. Reports of its natural …

Protection against oxidative damage caused by excessive reactive oxygen species (ROS)
by an antioxidant network is essential for the health of tissues, especially in the …