Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …

The increasing worldwide prevalence of obesity is partially related to the ready availability of
highly palatable foods which increases the incidence of hedonic, non-homeostatic feeding …

The search for a connection between diet and human cancer has a long history in cancer
research, as has interest in the mechanisms by which dietary factors might increase or …

Multiple theories identify neural vulnerability factors that may increase risk for overeating
and weight gain. Early cross-sectional neuroimaging studies were unable to determine …

Nutrition plays a key role in many aspects of health and dietary imbalances are major
determinants of chronic diseases including cardiovascular disease, obesity, diabetes and …

Objective: To identify the emotional and motivational processes that reinstate palatable food
intake following removal of high-fat diet (HFD) and associated neuroadaptations tied to …

Chronic disease is a major social challenge of the twenty-first century. In this review, we
examine the evidence for discordance between modern diets and those on which …

Obesity is associated with physical inactivity, which exacerbates the health consequences of
weight gain. However, the mechanisms that mediate this association are unknown. We …

In obesity, endocrine and metabolic perturbations, including those induced by chronic
activation of the hypothalamus–pituitary–adrenal axis, are associated with the accumulation …

Metabolism and nutrition have a significant role in epigenetic modifications such as DNA
methylation, which can influence gene expression. Recently, it has been suggested that …