In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer
diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora …

The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Macrocyclic chelators play a central role in medical imaging and nuclear medicine owing to
their unparalleled metal cation coordination abilities. Their functionalization by fluorinated …

Titanium-45 (45Ti) is a radionuclide with excellent physical characteristics for use in positron
emission tomography (PET) imaging, including a moderate half-life (3.08 h), decay by …

Recent clinical success with metal-based radiopharmaceuticals has sparked an interest in
the potential of these drugs for personalized medicine. Although often overlooked, the …

Radiolabeled antibodies are powerful tools for both imaging and therapy in the field of
nuclear medicine. Radiolabeling methods that do not release radionuclides from parent …

Nanogels open up access to a wide range of applications and offer among others hopeful
approaches for use in the field of biomedicine. This review provides a brief overview of …

Molecular imaging offers the possibility to investigate biological and biochemical processes
non-invasively and to obtain information on both anatomy and dysfunctions. Based on the …

Multispecific antibodies are engineered antibody derivatives that can bind to two or more
distinct epitopes or antigens. Unlike mixtures of monospecific antibodies, the binding …

The latest advancements in nuclear medicine indicate that radioactive isotopes and
associated metal chelators play crucial roles in the diagnosis and treatment of diseases. The …