Developing biomedical engineering technologies for reproductive medicine
Infertility is a rising global health issue with a far‐reaching impact on the socioeconomic
livelihoods. As there are highly complex causes of male and female infertility, it is highly …
livelihoods. As there are highly complex causes of male and female infertility, it is highly …
[HTML][HTML] Exosomes–Spectacular role in reproduction
A Kowalczyk, M Wrzecińska… - Biomedicine & …, 2022 - Elsevier
Exosomes are nano-sized structures that are found in semen, epididymal–fluid,
endometrium, as well as in follicular fluid. They are responsible for transporting bioactive …
endometrium, as well as in follicular fluid. They are responsible for transporting bioactive …
Very small embryonic-like stem cells (VSELs) regenerate whereas mesenchymal stromal cells (MSCs) rejuvenate diseased reproductive tissues
D Bhartiya, P Singh, D Sharma, A Kaushik - Stem Cell Reviews and …, 2022 - Springer
Compared to embryonic and induced pluripotent stem cells, mesenchymal stem/stromal
cells (MSCs) have made their presence felt with good therapeutic promise and safety profile …
cells (MSCs) have made their presence felt with good therapeutic promise and safety profile …
[HTML][HTML] The renaissance of male infertility management in the golden age of andrology
AE Calogero, R Cannarella, A Agarwal… - The world journal of …, 2023 - ncbi.nlm.nih.gov
Infertility affects nearly 186 million people worldwide and the male partner is the cause in
about half of the cases. Meta-regression data indicate an unexplained decline in sperm …
about half of the cases. Meta-regression data indicate an unexplained decline in sperm …
Understanding testicular single cell transcriptional atlas: from developmental complications to male infertility
MB Tirumalasetty, I Bhattacharya… - Frontiers in …, 2024 - frontiersin.org
Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …
Effect of monosodium glutamate on serum sex hormones and uterine histology in female rats along with its molecular docking and in-silico toxicity
Monosodium glutamate (MSG) is commonly used worldwide as a food flavour enhancer by
the food industry. The current study investigated the in vivo toxic effects of MSG on the uterus …
the food industry. The current study investigated the in vivo toxic effects of MSG on the uterus …
Engineered stem cell-based strategy: A new paradigm of next-generation stem cell product in regenerative medicine
H Han, BT Chen, Y Liu, Y Wang, L Xing, H Wang… - Journal of Controlled …, 2024 - Elsevier
Stem cells have garnered significant attention in regenerative medicine owing to their
abilities of multi-directional differentiation and self-renewal. Despite these encouraging …
abilities of multi-directional differentiation and self-renewal. Despite these encouraging …
A pumpless monolayer microfluidic device based on mesenchymal stem cell-conditioned medium promotes neonatal mouse in vitro spermatogenesis
Background Childhood cancer treatment-induced gonadotoxicity causes permanent
infertility/sub-infertility in nearly half of males. The current clinical and experimental …
infertility/sub-infertility in nearly half of males. The current clinical and experimental …
The current trend of exosome in epithelial ovarian cancer studies: A bibliometric review
N Baghban, M Ullah, I Nabipour - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer.
About 90% of ovary tumors are epithelial. The current treatment for EOC involves surgical …
About 90% of ovary tumors are epithelial. The current treatment for EOC involves surgical …
Preventing/reversing adverse effects of endocrine disruption on mouse testes by normalizing tissue resident VSELs
A Kaushik, SM Metkari, S Ali, D Bhartiya - Stem Cell Reviews and Reports, 2023 - Springer
Reproductive health of men is declining in today's world due to increased developmental
exposure to endocrine-disrupting chemicals (EDCs). We earlier reported that neonatal …
exposure to endocrine-disrupting chemicals (EDCs). We earlier reported that neonatal …