[HTML][HTML] Liquid biopsy for advanced NSCLC: a consensus statement from the international association for the study of lung cancer

C Rolfo, P Mack, GV Scagliotti, C Aggarwal… - Journal of Thoracic …, 2021 - Elsevier
Although precision medicine has had a mixed impact on the clinical management of patients
with advanced-stage cancer overall, for NSCLC, and more specifically for lung …

Independent drug action in combination therapy: implications for precision oncology

D Plana, AC Palmer, PK Sorger - Cancer discovery, 2022 - AACR
Combination therapies are superior to monotherapy for many cancers. This advantage was
historically ascribed to the ability of combinations to address tumor heterogeneity, but …

The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …

Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Evaluation of Advanced Lung Cancer

L Wang, G Tang, K Hu, X Liu, W Zhou, H Li, S Huang… - Radiology, 2022 - pubs.rsna.org
Background Gallium 68 (68Ga)–labeled fibroblast-activation protein inhibitor (FAPI) has
recently been introduced as a promising tumor imaging agent. Purpose To compare 68Ga …

Biomarker testing for patients with advanced non–small cell lung cancer: real-world issues and tough choices

NA Pennell, ME Arcila, DR Gandara… - American Society of …, 2019 - ascopubs.org
Over the last decade, the treatment of patients with advanced non–small cell lung cancer
(NSCLC) has become reliant on tissue and/or blood biomarkers to help guide treatment …

Safety and survival rates associated with ablative stereotactic radiotherapy for patients with oligometastatic cancer: a systematic review and meta-analysis

EJ Lehrer, R Singh, M Wang, VM Chinchilli… - JAMA …, 2021 - jamanetwork.com
Importance The oligometastatic paradigm postulates that patients with a limited number of
metastases can be treated with ablative local therapy to each site of disease with curative …

CRISPR/cas systems redefine nucleic acid detection: principles and methods

M Wang, R Zhang, J Li - Biosensors and Bioelectronics, 2020 - Elsevier
Methods that enable rapid, sensitive and specific analyses of nucleic acid sequences have
positive effects on precise disease diagnostics and effective clinical treatments by providing …

Molecular profiling for precision cancer therapies

ER Malone, M Oliva, PJB Sabatini, TL Stockley… - Genome medicine, 2020 - Springer
The number of druggable tumor-specific molecular aberrations has grown substantially in
the past decade, with a significant survival benefit obtained from biomarker matching …

Crocin inhibits angiogenesis and metastasis in colon cancer via TNF-α/NF-kB/VEGF pathways

HA Bakshi, GA Quinn, MM Nasef, V Mishra… - Cells, 2022 - mdpi.com
Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently
discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the …

Organoid sensitivity correlates with therapeutic response in patients with pancreatic cancer

JE Grossman, L Muthuswamy, L Huang… - Clinical Cancer …, 2022 - AACR
Purpose: Pancreatic ductal adenocarcinoma (PDAC) remains a significant health issue. For
most patients, there are no options for targeted therapy, and existing treatments are limited …