Reversed-phase liquid chromatography of peptides for bottom-up proteomics: a tutorial
J Lenco, S Jadeja, DK Naplekov… - Journal of Proteome …, 2022 - ACS Publications
The performance of the current bottom-up liquid chromatography hyphenated with mass
spectrometry (LC-MS) analyses has undoubtedly been fueled by spectacular progress in …
spectrometry (LC-MS) analyses has undoubtedly been fueled by spectacular progress in …
Core-shell particles lead the way to renewing high-performance liquid chromatography
In this review, we present the latest highlights and trends in the use of core-shell particles as
stationary phases in columns for liquid chromatography (LC). These highly homogeneous …
stationary phases in columns for liquid chromatography (LC). These highly homogeneous …
LC–MS bioanalysis of intact proteins and peptides
L Kang, N Weng, W Jian - Biomedical chromatography, 2020 - Wiley Online Library
Bioanalysis assays that reliably quantify biotherapeutics and biomarkers in biological
samples play pivotal roles in drug discovery and development. Liquid chromatography …
samples play pivotal roles in drug discovery and development. Liquid chromatography …
Sol‐Gel and Porous Glass‐Based Silica Monoliths with Hierarchical Pore Structure for Solid‐Liquid Catalysis
D Enke, R Gläser, U Tallarek - Chemie Ingenieur Technik, 2016 - Wiley Online Library
This work draws attention to both prospects and challenges for silica monoliths in solid‐
liquid catalysis at ultrahigh efficiency. The fundamental advantages of silica monoliths as …
liquid catalysis at ultrahigh efficiency. The fundamental advantages of silica monoliths as …
Computational investigation of longitudinal diffusion, eddy dispersion, and trans-particle mass transfer in bulk, random packings of core–shell particles with varied …
In recent years, chromatographic columns packed with core–shell particles have been
widely used for efficient and fast separations at comparatively low operating pressure …
widely used for efficient and fast separations at comparatively low operating pressure …
Simultaneous LC–MS determination of glucose regulatory peptides secreted by stem cell–derived islet organoids
For studying stem cell–derived islet organoids (SC‐islets) in an organ‐on‐chip (OoC)
platform, we have developed a reversed‐phase liquid chromatography–tandem mass …
platform, we have developed a reversed‐phase liquid chromatography–tandem mass …
[HTML][HTML] Determination of insulin secretion from stem cell-derived islet organoids with liquid chromatography-tandem mass spectrometry
Organoids are laboratory-grown 3D organ models, mimicking human organs for eg drug
development and personalized therapy. Islet organoids (typically 100–200 µm), which can …
development and personalized therapy. Islet organoids (typically 100–200 µm), which can …
Speed-resolution properties of columns packed with new 4.6 μm Kinetex-C18 core–shell particles
F Gritti, G Guiochon - Journal of Chromatography A, 2013 - Elsevier
The achievable separation speed and resolution of columns packed with the new 4.6 μm
Kinetex particles were characterized by their permeability and their plate heights, measured …
Kinetex particles were characterized by their permeability and their plate heights, measured …
New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins
This review paper discusses the success of columns packed with superficially porous
particles (SPP) in liquid chromatography for the analysis of peptides and proteins. First, it …
particles (SPP) in liquid chromatography for the analysis of peptides and proteins. First, it …
Rapid development of core–shell column technology: accurate measurements of the intrinsic column efficiency of narrow-bore columns packed with 4.6 down to 1.3 …
F Gritti, G Guiochon - Journal of Chromatography A, 2014 - Elsevier
The intrinsic heights equivalent to a theoretical plate (HETPs) of 31 narrow-bore and wide-
bore columns packed with four different brands of core–shell particles were accurately …
bore columns packed with four different brands of core–shell particles were accurately …