[HTML][HTML] Computational modeling of the human auditory periphery: Auditory-nerve responses, evoked potentials and hearing loss
S Verhulst, A Altoe, V Vasilkov - Hearing research, 2018 - Elsevier
Abstract Models of the human auditory periphery range from very basic functional
descriptions of auditory filtering to detailed computational models of cochlear mechanics …
descriptions of auditory filtering to detailed computational models of cochlear mechanics …
Unified cochlear model for low-and high-frequency mammalian hearing
The spatial variations of the intricate cytoarchitecture, fluid scalae, and mechano-electric
transduction in the mammalian cochlea have long been postulated to provide the organ with …
transduction in the mammalian cochlea have long been postulated to provide the organ with …
Enhancing the sensitivity of the envelope-following response for cochlear synaptopathy screening in humans: The role of stimulus envelope
V Vasilkov, M Garrett, M Mauermann, S Verhulst - Hearing Research, 2021 - Elsevier
Auditory de-afferentation, a permanent reduction in the number of inner-hair-cells and
auditory-nerve synapses due to cochlear damage or synaptopathy, can reliably be …
auditory-nerve synapses due to cochlear damage or synaptopathy, can reliably be …
A convolutional neural-network framework for modelling auditory sensory cells and synapses
In classical computational neuroscience, analytical model descriptions are derived from
neuronal recordings to mimic the underlying biological system. These neuronal models are …
neuronal recordings to mimic the underlying biological system. These neuronal models are …
Predicting synapse counts in living humans by combining computational models with auditory physiology
BN Buran, GP McMillan, S Keshishzadeh… - The Journal of the …, 2022 - pubs.aip.org
Aging, noise exposure, and ototoxic medications lead to cochlear synapse loss in animal
models. As cochlear function is highly conserved across mammalian species, synaptopathy …
models. As cochlear function is highly conserved across mammalian species, synaptopathy …
Phase locking of auditory nerve fibers: the role of lowpass filtering by hair cells
AJ Peterson, P Heil - Journal of Neuroscience, 2020 - Soc Neuroscience
Phase locking of auditory-nerve-fiber (ANF) responses to the temporal fine structure of
acoustic stimuli, a hallmark of the auditory system's temporal precision, is important for many …
acoustic stimuli, a hallmark of the auditory system's temporal precision, is important for many …
Optimized tuning of auditory inner hair cells to encode complex sound through synergistic activity of six independent K+ current entities
M Dierich, A Altoe, J Koppelmann, S Evers… - Cell Reports, 2020 - cell.com
Auditory inner hair cells (IHCs) convert sound vibrations into receptor potentials that drive
synaptic transmission. For the precise encoding of sound qualities, receptor potentials are …
synaptic transmission. For the precise encoding of sound qualities, receptor potentials are …
[HTML][HTML] Characterization of the decline in auditory nerve phase locking at high frequencies
The frequency dependence of phase locking in the auditory nerve influences various
auditory coding mechanisms. The decline of phase locking with increasing frequency is …
auditory coding mechanisms. The decline of phase locking with increasing frequency is …
Towards a differential diagnosis of cochlear synaptopathy and outer-hair-cell deficits in mixed sensorineural hearing loss pathologies
V Vasilkov, S Verhulst - medRxiv, 2019 - medrxiv.org
Damage to the auditory periphery is more widespread than predicted by the gold-standard
clinical audiogram. Noise exposure, ototoxicity and aging can destroy cochlear inner-hair …
clinical audiogram. Noise exposure, ototoxicity and aging can destroy cochlear inner-hair …
Phase locking of auditory-nerve fibers reveals stereotyped distortions and an exponential transfer function with a level-dependent slope
AJ Peterson, P Heil - Journal of Neuroscience, 2019 - Soc Neuroscience
Phase locking of auditory-nerve-fiber (ANF) responses to the fine structure of acoustic stimuli
is a hallmark of the auditory system's temporal precision and is important for many aspects of …
is a hallmark of the auditory system's temporal precision and is important for many aspects of …