Transposable elements: major players in shaping genomic and evolutionary patterns

N Colonna Romano, L Fanti - Cells, 2022 - mdpi.com
Transposable elements (TEs) are ubiquitous genetic elements, able to jump from one
location of the genome to another, in all organisms. For this reason, on the one hand, TEs …

Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases

SAM Sherazi, A Abbasi, A Jamil, M Uzair… - Neural Regeneration …, 2023 - journals.lww.com
Aging is linked to the deterioration of many physical and cognitive abilities and is the leading
risk factor for Alzheimer's disease. The growing aging population is a significant healthcare …

Evolutionary dynamics between transposable elements and their host genomes: mechanisms of suppression and escape

MA Lawlor, CE Ellison - Current Opinion in Genetics & Development, 2023 - Elsevier
Transposable elements (TEs) are ubiquitous among eukaryotic species. Their evolutionary
persistence is likely due to a combination of tolerogenic, evasive/antagonistic, and …

Telomeres and their neighbors

LP Jenner, V Peska, J Fulnečková, E Sýkorová - Genes, 2022 - mdpi.com
Telomeres are essential structures formed from satellite DNA repeats at the ends of
chromosomes in most eukaryotes. Satellite DNA repeat sequences are useful markers for …

Rapid evolution at the Drosophila telomere: transposable element dynamics at an intrinsically unstable locus

MP McGurk, AM Dion-Côté, DA Barbash - Genetics, 2021 - academic.oup.com
Drosophila telomeres have been maintained by three families of active transposable
elements (TEs), HeT-A, TAHRE, and TART, collectively referred to as HTTs, for tens of …

Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing

M Cui, Y Bai, K Li, YS Rong - PLoS Genetics, 2021 - journals.plos.org
Drosophila chromosomes are elongated by retrotransposon attachment, a process poorly
understood. Here we characterized a mutation affecting the HipHop telomere-capping …

Different transcriptional responses by the CRISPRa system in distinct types of heterochromatin in Drosophila melanogaster

A Ortega-Yáñez, S Cruz-Ruiz, M Vázquez, M Zurita - Scientific Reports, 2022 - nature.com
Transcription factors (TFs) activate gene expression by binding to elements close to
promoters or enhancers. Some TFs can bind to heterochromatic regions to initiate gene …

[PDF][PDF] Transposable Elements: Major Players in Shaping Genomic and Evolutionary Patterns. Cells 2022, 11, 1048

N Colonna Romano, L Fanti - 2022 - academia.edu
Transposable elements (TEs) are ubiquitous genetic elements, able to jump from one
location of the genome to another, in all organisms. For this reason, on the one hand, TEs …