The role of non-coding RNAs in oncology

FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …

[HTML][HTML] Multiparametric MRI for prostate cancer diagnosis: current status and future directions

A Stabile, F Giganti, AB Rosenkrantz, SS Taneja… - Nature reviews …, 2020 - nature.com
The current diagnostic pathway for prostate cancer has resulted in overdiagnosis and
consequent overtreatment as well as underdiagnosis and missed diagnoses in many men …

Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

[HTML][HTML] The emerging role of lncRNAs in cancer

M Huarte - Nature medicine, 2015 - nature.com
It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …

[HTML][HTML] Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

The functions and unique features of LncRNAs in cancer development and tumorigenesis

K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …

Potential of long non‐coding RNAs in cancer patients: from biomarkers to therapeutic targets

S Chandra Gupta… - International journal of …, 2017 - Wiley Online Library
Because of high specificity and easy detection in the tissues, serum, plasma, urine and
saliva, interest in exploring the potential of long non‐coding RNAs (lncRNAs) in cancer …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …

Biomarkers for prostate cancer: prostate-specific antigen and beyond

MJ Duffy - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In recent years, several new biomarkers supplementing the role of prostate-specific antigen
(PSA) have become available for men with prostate cancer. Although widely used in an ad …

The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …