Melittin, a major peptide component of bee venom, and its conjugates in cancer therapy
Melittin (MEL), a major peptide component of bee venom, is an attractive candidate for
cancer therapy. This agent has shown a variety of anti-cancer effects in preclinical cell …
cancer therapy. This agent has shown a variety of anti-cancer effects in preclinical cell …
Applications and evolution of melittin, the quintessential membrane active peptide
Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer
Despite decades of study, the molecular mechanisms and selectivity of the biomolecular
components of honeybee (Apis mellifera) venom as anticancer agents remain largely …
components of honeybee (Apis mellifera) venom as anticancer agents remain largely …
Bee venom in cancer therapy
N Oršolić - Cancer and metastasis reviews, 2012 - Springer
Abstract Bee venom (BV)(api-toxin) has been widely used in the treatment of some immune-
related diseases, as well as in recent times in treatment of tumors. Several cancer cells …
related diseases, as well as in recent times in treatment of tumors. Several cancer cells …
Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds
Bee venom (BV) therapy (BVT), the therapeutic application of BV, has been used in
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …
traditional medicine to treat diseases, such as arthritis, rheumatism, pain, cancerous tumors …
Anti-inflammatory applications of melittin, a major component of bee venom: detailed mechanism of action and adverse effects
Inflammation is a pervasive phenomenon triggered by the innate and adaptive immune
systems to maintain homeostasis. The phenomenon normally leads to recovery from …
systems to maintain homeostasis. The phenomenon normally leads to recovery from …
[HTML][HTML] Review of the anticancer activities of bee products
P Premratanachai, C Chanchao - Asian Pacific journal of tropical …, 2014 - Elsevier
Bee products have long been used in traditional medicine. The raw materials, crude extracts
and purified active compounds from them have been found to exhibit interesting …
and purified active compounds from them have been found to exhibit interesting …
Chemical characterization, antioxidant, anti-inflammatory and cytotoxic properties of bee venom collected in Northeast Portugal
F Sobral, A Sampaio, S Falcão, MJRP Queiroz… - Food and Chemical …, 2016 - Elsevier
Bee venom (BV) or apitoxin is a complex mixture of substances with reported biological
activity. In the present work, five bee venom samples obtained from Apis mellifera iberiensis …
activity. In the present work, five bee venom samples obtained from Apis mellifera iberiensis …
The nociceptive and anti-nociceptive effects of bee venom injection and therapy: a double-edged sword
J Chen, WR Lariviere - Progress in neurobiology, 2010 - Elsevier
Bee venom injection as a therapy, like many other complementary and alternative medicine
approaches, has been used for thousands of years to attempt to alleviate a range of …
approaches, has been used for thousands of years to attempt to alleviate a range of …
[HTML][HTML] Arthropod venoms and cancer
TE Heinen, ABG da Veiga - Toxicon, 2011 - Elsevier
Many active principles produced by animals, plants and microorganisms have been
employed in the development of new drugs to treat diseases such as cancer. Among the …
employed in the development of new drugs to treat diseases such as cancer. Among the …