The cyanine dyes are among the oldest classes of synthetic compounds but continue to find
applications in a variety of fields. In many cases, the dyes act as fluorescent labels for …

It is known that polymethine dyes (PD) can form complexes with biomacromolecules, in
which, as a rule, fluorescence buildup is observed. In addition, PD possess a unique …

The synthesis, proof of structure, and the absorption and fluorescence properties of two new
unsymmetrical cyanine dyes, thiazole orange dimer (TOTO; 1, 1′-(4, 4, 7, 7-tetramethyl-4, 7 …

Methods and apparatus for implementing microfluidic analysis devices are provided. A
monolithic elastomer membrane associated with an integrated pneumatic manifold allows …

The absorption and fluorescence spectra, fluorescence quantum yields, lifetimes and time‐
resolved fluorescence spectra are reported for nine different fluorescent DNA‐dyes. The …

Methods and apparatus for genome analysis are provided. A microfabricated structure
including a microfluidic distribu tion channel is configured to distribute microreactor …

A DNA sequencing method is presented that utilizes capillary array electrophoresis, two-
color fluorescence detection, and a two-dye labeling protocol. SangerDNA sequencing …

Thiazole orange homodimer (TOTO; 1, 1′-(4, 4, 7, 7-tetramethyl-4, 7-
diazaundecamethylene)-bis-4-[3-methyl-2, 3-dihydro-(benzo-1, 3-thiazole)-2-methylidene] …

Interaction of Thiazole Orange (TO) with double-, triple-, and quadruple-stranded forms of
DNA was studied. We have demonstrated by UV− vis absorption, circular dichroism (CD) …

Gene functional analyses have proceeded remarkably in the fields of molecular biology,
pharmacogenomics, and clinical research, on the basis of completion of the decoding of the …