Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer's disease
(AD), and its accumulation has been considered as the molecular driver of Alzheimer's …

Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Alzheimer's disease (AD) is characterized pathologically by amyloid-beta (Aβ) deposition in
brain parenchyma and blood vessels (as cerebral amyloid angiopathy (CAA)) and by …

Amyloid-ß (Aß) is best known as the misfolded peptide that is involved in the pathogenesis
of Alzheimer's disease (AD), and it is currently the primary therapeutic target in attempts to …

A single traumatic brain injury is associated with an increased risk of dementia and, in a
proportion of patients surviving a year or more from injury, the development of hallmark …

Over the past 70 years, diffuse axonal injury (DAI) has emerged as one of the most common
and important pathological features of traumatic brain injury (TBI). Axons in the white matter …

Traumatic brain injury (TBI) has long been recognized to be a risk factor for dementia. This
association has, however, only recently gained widespread attention through the increased …

The acute and long-term consequences of traumatic brain injury (TBI) have received
increased attention in recent years. In this Review, we discuss the neuropathology and …

Mild traumatic brain injury (TBI), which is defined as a head trauma resulting in a brief loss of
consciousness and/or alteration of mental state, is usually benign, but occasionally causes …

Brain temperature, as an independent therapeutic target variable, has received increasingly
intense clinical attention. To date, brain hypothermia represents the most potent …