Origins of specificity in protein-DNA recognition

R Rohs, X Jin, SM West, R Joshi… - Annual review of …, 2010 - annualreviews.org
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

Watson–Crick versus Hoogsteen base pairs: chemical strategy to encode and express genetic information in life

S Takahashi, N Sugimoto - Accounts of chemical research, 2021 - ACS Publications
Conspectus Nucleic acids typically form a double helix structure through Watson–Crick base-
pairing. In contrast, non-Watson–Crick base pairs can form other three-dimensional …

Molecular structure of a left-handed double helical DNA fragment at atomic resolution

AHJ Wang, GJ Quigley, FJ Kolpak, JL Crawford… - Nature, 1979 - nature.com
The DNA fragment d (CpGpCpGpCpG) crystallises as a left-handed double helical molecule
with Watson–Crick base pairs and an antiparallel organisation of the sugar phosphate …

Sequence-specific recognition of double helical nucleic acids by proteins.

NC Seeman, JM Rosenberg… - Proceedings of the …, 1976 - National Acad Sciences
The base pairs in double helical nucleic acids have been compared to see how they can be
recognized by proteins. We conclude that a single hydrogen bond is inadequate for uniquely …

CURVES+ web server for analyzing and visualizing the helical, backbone and groove parameters of nucleic acid structures

C Blanchet, M Pasi, K Zakrzewska… - Nucleic acids …, 2011 - academic.oup.com
Curves+, a revised version of the Curves software for analyzing the conformation of nucleic
acid structures, is now available as a web server. This version, which can be freely accessed …

RNA double-helical fragments at atomic resolution: I. The crystal and molecular structure of sodium adenylyl-3′, 5′-uridine hexahydrate

NC Seeman, JM Rosenberg, FL Suddath… - Journal of molecular …, 1976 - Elsevier
The crystal structure of sodium adenylyl-3′, 5′-uridine (ApU) hexahydrate has been
determined by X-ray diffraction procedures and refined to an R factor of 0.057. ApU …

RNA double-helical fragments at atomic resolution: II. The crystal structure of sodium guanylyl-3′, 5′-cytidine nonahydrate

JM Rosenberg, NC Seeman, RO Day, A Rich - Journal of molecular biology, 1976 - Elsevier
The crystal structure of sodium guanylyl-3′, 5′-cytidine (GpC) nonahydrate has been
determined by X-ray diffraction procedures and refined to an R value of 0.054. GpC …

A third mode of DNA binding: phosphate clamps by a polynuclear platinum complex

S Komeda, T Moulaei, KK Woods… - Journal of the …, 2006 - ACS Publications
We describe a 1.2 Å X-ray structure of a double-stranded B-DNA dodecamer (the Dickerson
Dodecamer, DDD,[d (CGCGAATTCGCG)] 2) associated with a cytotoxic platinum (II) …

Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound

AHJ Wang, J Nathans, G Van der Marel, JH Van Boom… - Nature, 1978 - nature.com
The crystal structure of a complex containing deoxy CpG and a terpyridine platinum
compound (TPH) shows a DNA double helical fragment with TPH intercalated between two …

A new antitumoral agent: 9-hydroxyellipticine. Possibility of a rational design of anticancerous drugs in the series of DNA intercalating drugs

JB Le Pecq, Nguyen-Dat-Xuong… - Proceedings of the …, 1974 - National Acad Sciences
The designing of DNA intercalating drugs with high DNA affinity in the series of ellipticine
has led to a new antitumoral agent, 9-hydroxyellipticine, which has a high DNA affinity, a …