The persistence of increased excitability and spontaneous activity in injured peripheral
neurons is imperative for the development and persistence of many forms of neuropathic …

It is often difficult to regain neurological function following spinal cord injury (SCI).
Neuroinflammation is thought to be responsible for this failure. Regulating the inflammatory …

Spinal cord injury (SCI) in humans frequently causes intractable chronic pain. Females are
susceptible to worse pain than males, and females may show higher pain prevalence after …

Spinal cord injury (SCI) occurs when the spinal cord is damaged from either a traumatic
event or disease. SCI is characterised by multiple injury phases that affect the transmission …

Spinal cord injury (SCI) is a traumatic disease resulting in neuronal injury. circRNAs are
closely associated with human diseases. Nevertheless, the potential mechanism by which …

Chronic pain is a major public health problem and an economic burden worldwide.
However, its underlying pathological mechanisms remain unclear. MicroRNAs (miRNAs) are …

Spinal cord injury (SCI) is a fatal and intractable disease accompanied by the comorbidity of
chronic neuropathic pain. Here, we purposed to explore the therapeutic effect and the …

Aged individuals with spinal cord injury (SCI) are prevalent with increased mortality and
worse outcomes. SCI can cause secondary brain neuroinflammation and …

Patients with neuropathic pain are heterogeneous in pathophysiology, etiology, and clinical
presentation. Signs and symptoms are determined by the nature of the injury and factors …

The progressive worsening of disc degeneration and related nonspecific back pain are
prominent clinical issues that cause a tremendous economic burden. Activation of reactive …