Retinal development in teleosts can broadly be divided into three epochs. The first is the
specification of cellular domains in the larval forebrain that give rise to the retinal primordia …

The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Second only to the mouse and rat, the zebrafish is the most popular animal model in
biomedical research. Rapid embryonic development and transparent organogenesis give it …

In the absence of external cues, neurons in vitro polarize by using intrinsic mechanisms. For
example, cultured hippocampal neurons extend arbitrarily oriented neurites and then one of …

Nuclear receptors (NRs) are transcription factors that are implicated in several biological
processes such as embryonic development, homeostasis, and metabolic diseases. To study …

Background The disorder of copper homeostasis is linked with disease and developmental
defects, and excess copper_nanoparticles (CuNPs) and ion (Cu 2+) will induce …

The Wnt-signaling pathway is a known regulator of stem cell maintenance, cellular
proliferation and differentiation, and cancer development in various tissues. Wnt proteins …

The orderly packing and precise arrangement of epithelial cells is essential to the
functioning of many tissues, and refinement of this packing during development is a central …

Notch–Delta signaling has been implicated in several alternative modes of function in the
vertebrate retina. To further investigate these functions, we examined retinas from zebrafish …

In the developing zebrafish retina, neurogenesis is initiated in cells adjacent to the optic
stalk and progresses to the entire neural retina. It has been reported that hedgehog (Hh) …