[PDF][PDF] Bone morphogenetic proteins: From discovery to development of a novel autologous bone graft substitute consisting of recombinant human BMP6 delivered in …

S Vukičević - This is an open-access article distributed under the …, 2020 - rad-med.com
Bone Morphogenetic Proteins (BMPs) are growth and differentiation factors within the TGFβ
superfamily of proteins. They induce ectopic and orthotopic endochondral bone formation …

[HTML][HTML] A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with …

D Durdevic, T Vlahovic, S Pehar, D Miklic… - Bone, 2020 - Elsevier
Bone morphogenetic proteins (BMPs) are known to induce new bone formation in vivo but
treating trabecular bone defects with a BMP based therapeutic remains controversial. Here …

Recombinant human bone morphogenetic protein 6 delivered within autologous blood coagulum restores critical size segmental defects of ulna in rabbits

L Grgurevic, H Oppermann, M Pecin, I Erjavec… - JBMR …, 2019 - Wiley Online Library
ABSTRACT BMP2 and BMP7, which use bovine Achilles tendon–derived absorbable
collagen sponge and bovine bone collagen as scaffold, respectively, have been approved …

A cell-based combination product for the repair of large bone defects

J Lammens, M Maréchal, H Delport, L Geris… - Bone, 2020 - Elsevier
Regenerative cell-based implants using periosteum-derived stem cells were developed for
the treatment of large 3 cm fresh and 4.5 centimeter biological compromised bone gaps in a …

Copresentation of BMP-6 and RGD ligands enhances cell adhesion and BMP-mediated signaling

F Posa, AL Grab, V Martin, D Hose, A Seckinger… - Cells, 2019 - mdpi.com
We report on the covalent immobilization of bone morphogenetic protein 6 (BMP-6) and its
co-presentation with integrin ligands on a nanopatterned platform to study cell adhesion and …

Koštani morfogenetski proteini (BMP): Od otkrića do razvoja nove autologne koštane naprave koja se sastoji od rekombinantnog humanog BMP6 u autolognom …

S Vukičević, M Perić, H Oppermann… - … akademije znanosti i …, 2020 - hrcak.srce.hr
Koštani morfogenetski proteini (BMP) čine grupu čimbenika rasta i diferencijacije unutar
TGFβ nado-bitelji. Oni induciraju stvaranje ektopične i ortotopične endohondralne kosti te su …

OSTEOGROW–novel bone device for bone regeneration

L Grgurević, S Vukičević - Rad Hrvatske akademije znanosti i …, 2018 - hrcak.srce.hr
Sažetak Molecular processes required for bone repair are a prerequisite for the
development of new biological procedures for stimulation of bone healing. Currently, there is …