Alzheimer's disease (AD) is a neurodegenerative disease with high morbidity and mortality,
for which there is no available cure. Currently, it is generally believed that AD is a disease …

This article is a systematic review of reverse screening methods used to search for the
protein targets of chemopreventive compounds or drugs. Typical chemopreventive …

Cardiovascular diseases (CVDs) and neurological diseases are widespread diseases with
substantial rates of morbidity and mortality around the world. For the past few years, the …

In silico target fishing, whose aim is to identify possible protein targets for a query molecule,
is an emerging approach used in drug discovery due its wide variety of applications. This …

Background Alzheimer's disease (AD) is the most prevalent form of dementia and represents
one of the highest unmet requirements in medicine today. There is shortage of novel …

Increasing human life expectancy prompts the development of novel remedies for cognitive
decline: 44 million people worldwide are affected by dementia, and this number is predicted …

The purpose of the current study was to explore the effects of the water extracts of Epimedii
Folium and Curculiginis Rhizoma (EX) on Aβ-induced Alzheimer's disease. Aβ 1-42 was …

Based on compelling experimental and clinical evidence, the fruit of Lycium ruthenicum
Murr.(LRM), a unique traditional Tibetan medicine, exerts beneficial effects on ameliorating …

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by
progressive loss of motor neurons. There are no definitive pathogenic mechanisms and …

Metabolic syndrome (MS) is becoming a worldwide health problem. Wendan decoction
(WDD)—a famous traditional Chinese medicine formula—has been extensively employed to …