Inflammation in obesity, diabetes, and related disorders

TV Rohm, DT Meier, JM Olefsky, MY Donath - Immunity, 2022 - cell.com
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy

G Sloan, D Selvarajah, S Tesfaye - Nature Reviews Endocrinology, 2021 - nature.com
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Acarbose treatment affects the serum levels of inflammatory cytokines and the gut content of bifidobacteria in C hinese patients with type 2 diabetes mellitus: 阿卡波糖 …

B Su, H Liu, J Li, Y Sunli, B Liu, D Liu… - Journal of …, 2015 - Wiley Online Library
摘要背景: 研究对中国2 型糖尿病患者在常规治疗的基础上加用阿卡波糖后对患者粪便肠道菌群
及血清炎症因子的影响. 方法: 95 名2 型糖尿病患者在常规治疗的基础上随机分为两组, A 组59 …

Chronic low grade inflammation in pathogenesis of PCOS

E Rudnicka, K Suchta, M Grymowicz… - International journal of …, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is a one of the most common endocrine disorders, with a
prevalence rate of 5–10% in reproductive aged women. It's characterized by (1) chronic …

The metabolic nature of inflammatory bowel diseases

TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022 - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

[HTML][HTML] Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links

OO Oguntibeju - International journal of physiology …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

Adipose tissue dysfunction as determinant of obesity-associated metabolic complications

M Longo, F Zatterale, J Naderi, L Parrillo… - International journal of …, 2019 - mdpi.com
Obesity is a critical risk factor for the development of type 2 diabetes (T2D), and its
prevalence is rising worldwide. White adipose tissue (WAT) has a crucial role in regulating …

[HTML][HTML] The role of inflammation in diabetes: current concepts and future perspectives

S Tsalamandris, AS Antonopoulos… - European cardiology …, 2019 - ncbi.nlm.nih.gov
Diabetes is a complex metabolic disorder affecting the glucose status of the human body.
Chronic hyperglycaemia related to diabetes is associated with end organ failure. The clinical …