A review: Biologically active 3, 4-heterocycle-fused coumarins
The combination of heterocycles offers a new opportunity to create novel multicyclic
compounds having improved biological activity. Coumarins are ubiquitous natural …
compounds having improved biological activity. Coumarins are ubiquitous natural …
Coumarin hybrids as novel therapeutic agents
Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …
A review on pharmacological properties of coumarins
D Srikrishna, C Godugu… - Mini reviews in medicinal …, 2018 - ingentaconnect.com
The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural
products, displays diverse pharmacological properties. It has attracted the attention of …
products, displays diverse pharmacological properties. It has attracted the attention of …
Recent advances in the synthesis of coumarin derivatives via Knoevenagel condensation: A review
RH Vekariya, HD Patel - Synthetic Communications, 2014 - Taylor & Francis
The synthesis of coumarins through Knoevenagel condensation is one of the most important
processes in synthetic organic chemistry and medicinal chemistry. Compounds including a …
processes in synthetic organic chemistry and medicinal chemistry. Compounds including a …
Synthesis and in vitro evaluation of novel coumarin–chalcone hybrids as potential anticancer agents
A series of coumarin–chalcone hybrids have been synthesized and evaluated for their in
vitro cytotoxicity against a panel of four human cancer cell lines and normal fibroblasts …
vitro cytotoxicity against a panel of four human cancer cell lines and normal fibroblasts …
New frontiers in selective human MAO-B inhibitors: miniperspective
S Carradori, R Silvestri - Journal of medicinal chemistry, 2015 - ACS Publications
Accumulating evidence shows a relationship between the human MAO-B (hMAO-B) enzyme
and neuropsychiatric/degenerative disorder, personality traits, type II alcoholism, borderline …
and neuropsychiatric/degenerative disorder, personality traits, type II alcoholism, borderline …
The structure and pharmacological functions of coumarins and their derivatives
L Wu, X Wang, W Xu, F Farzaneh… - Current medicinal …, 2009 - ingentaconnect.com
Coumarins are of many different structures. They constitute an important class of
pharmacological agents possessing a range of different physiological activities including …
pharmacological agents possessing a range of different physiological activities including …
Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …
Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents
F Belluti, G Fontana, L Dal Bo, N Carenini… - Bioorganic & medicinal …, 2010 - Elsevier
The naturally occurring coumarins and resveratrol, attract great attention due to their wide
range of biological properties, including anticancer, antileukemic, antibacterial and anti …
range of biological properties, including anticancer, antileukemic, antibacterial and anti …
Coumarin hybrid derivatives as promising leads to treat tuberculosis: Recent developments and critical aspects of structural design to exhibit anti-tubercular activity
Tuberculosis (TB) is a highly contagious airborne disease with nearly 25% of the world's
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …
population infected with it. Challenges such as multi drug resistant TB (MDR-TB), extensive …