Successful pregnancy relies on maternal immunologic tolerance mechanisms limit
maladaptive immune responses against the semi-allogeneic fetus and placenta and support …

Background The incidence of food allergy has been increasing in recent years, but the
prevention, diagnosis, and treatment of food allergy remain challenges in the world. Food …

Background Identification of target antigens PLA2R, THSD7A, NELL1, or Semaphorin-3B
can explain the majority of cases of primary membranous nephropathy (MN). However …

Intrathecal immunoglobulin G (IgG) synthesis and oligoclonal IgG bands in cerebrospinal
fluid (CSF) are hallmarks of multiple sclerosis (MS), but the antigen specificities remain …

The underlying molecular mechanisms of autoimmune diseases are poorly understood. To
unravel the autoimmune processes across diseases, comprehensive and unbiased …

Profiling the autoantibody repertoire with large antigen collections is emerging as a powerful
tool for the identification of biomarkers for autoimmune diseases. Here, a systematic and …

The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the
majority of primary (idiopathic) cases of membranous nephropathy (MN) has been followed …

Autoantibodies are a key component for the diagnosis, prognosis and monitoring of various
diseases. In order to discover novel autoantibody targets, highly multiplexed assays based …

Autism spectrum disorder (ASD) is an important health issue and affects 1 in 59 children in
the US. Prior studies determined that maternal autoantibody related (MAR) autism is thought …

Morphea and other scleroderma-like skin conditions are occasionally linked with exposure
to chemical compounds such as silicone. We treated a 56-year-old woman with generalized …