BACKGROUND Diabetic foot ulcers are a common diabetic complication leading to
alarming figures of amputation, disability, and early mortality. The diabetic glucooxidative …

Venous leg ulcers, diabetic foot ulcers, and pressure ulcers are complex chronic wounds
with multifactorial etiologies that are associated with high patient morbidity and mortality …

A growing body of evidence suggests that the interaction between immune and metabolic
responses is essential for maintaining tissue and organ homeostasis. These interacting …

Aging increases the susceptibility to a diverse set of diseases and disorders, including
neurodegeneration, cancer, diabetes, and arthritis. Natural compounds are currently being …

Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

Cellular senescence is a stress-response mechanism implicated in various physiological
processes, diseases, and aging. Current detection approaches have partially addressed the …

Chronic non-healing wounds have posed a severe threat to patients mentally and
physically. Behavior dysregulation of remaining cells at wound sites is recognized as the …

Chronic wounds develop when the orderly process of cutaneous wound healing is delayed
or disrupted. Development of a chronic wound is associated with significant morbidity and …

Simple Summary The biology of cellular senescence has broad implications for the fields of
aging, tissue and wound repair, tumor biology, and development. Cellular senescence is a …

The vasculature is comprised of endothelial cells that are heterogeneous in nature. From
tissue resident progenitors to mature differentiated endothelial cells, the diversity of these …