Adverse pregnancy outcomes (APOs)—including pre-term birth, pre-eclampsia, and
intrauterine growth restriction—are common interrelated disorders caused by placental …

The prevalence of obesity is increasingly common in the United States, with~ 25% of women
of reproductive age being overweight or obese. Metaflammation, a chronic low grade …

Background Recent studies have suggested that bacteria associated with the placenta—a
“placental microbiome”—may be important in reproductive health and disease. However, a …

OBJECTIVE: To estimate whether sleep-disordered breathing during pregnancy is a risk
factor for the development of hypertensive disorders of pregnancy and gestational diabetes …

OBJECTIVE: To assess the relationships between self-reported psychosocial stress and
preterm birth, hypertensive disease of pregnancy, and small-for-gestational-age (SGA) birth …

Importance Spontaneous preterm birth is a leading cause of infant mortality. Prediction,
largely based on prior pregnancy outcomes, is not possible in women pregnant for the first …

Background Experimental and epidemiologic data suggest that among nonpregnant adults,
sleep duration may be an important risk factor for chronic disease. Although pregnant …

Anatomical, physiological, psychological and hormonal alterations affect sleep during
pregnancy. Sleep appears tobe commonly impaired only after the first trimester. Albeit …

OBJECTIVE: To characterize prescription and other medication use in a geographically and
ethnically diverse cohort of women in their first pregnancy. METHODS: In a prospective …

Background Identifying pregnancy‐associated risk factors before the development of major
cardiovascular disease events could provide opportunities for prevention. The objective of …