A simple, time-and cost-effective, high-throughput depletion strategy for deep plasma proteomics

A Viode, P van Zalm, KK Smolen, B Fatou… - Science …, 2023 - science.org
We introduce a cost-effective, robust high-throughput–compatible plasma depletion method
enabling in-depth profiling of plasma that detects> 1300 proteins per run with a throughput …

Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients

J Diray-Arce, S Fourati, ND Jayavelu, R Patel… - Cell Reports …, 2023 - cell.com
The IMPACC cohort, composed of> 1,000 hospitalized COVID-19 participants, contains five
illness trajectory groups (TGs) during acute infection (first 28 days), ranging from milder (TG1 …

MD–ligand–receptor: a high-performance computing tool for characterizing ligand–receptor binding interactions in molecular dynamics trajectories

M Pieroni, F Madeddu, J Di Martino, M Arcieri… - International Journal of …, 2023 - mdpi.com
Molecular dynamics simulation is a widely employed computational technique for studying
the dynamic behavior of molecular systems over time. By simulating macromolecular …

Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes

A Viode, KK Smolen, P van Zalm, D Stevenson… - Science …, 2024 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …

Analytical challenges in omics research on asthma and allergy: A National Institute of Allergy and Infectious Diseases workshop

S Bunyavanich, PM Becker, MC Altman… - Journal of Allergy and …, 2024 - Elsevier
Studies of asthma and allergy are generating increasing volumes of omics data for analysis
and interpretation. The National Institute of Allergy and Infectious Diseases (NIAID) …