Critical limb ischemia (CLI), the most severe form of peripheral artery disease, is
characterized by pain at rest and non-healing ulcers in the lower extremities. For patients …

The age-adjusted prevalence of peripheral arterial disease in the US population has been
estimated to approach 12%. The clinical consequences of occlusive peripheral arterial …

Based on the increasingly understood regenerative capacity of the human heart and
vascular system, 1 cardiovascular regenerative medicine (CRM) encompasses all potential …

Objective/Background Critical limb ischemia (CLI) is the most advanced stage of peripheral
artery disease (PAD), and many patients with CLI are not eligible for conventional …

Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Stem cell therapy is a promising approach for the treatment of tissue ischemia associated
with myocardial infarction and peripheral arterial disease. Stem and progenitor cells derived …

Background: Critical Limb Ischemia (CLI) is the most advanced stage of peripheral arterial
disease and is usually treated with bypass surgery or endovascular revascularization …

Chronic critical limb ischemia (CLI) represents an end-stage manifestation of peripheral
arterial disease (PAD). CLI patients are at very high risk of amputation and cardiovascular …

Background Diabetic foot (DF) is one of the most common and serious complications of
diabetes mellitus (DM), which brings great psychological and economic pressure to patients …

Peripheral blood is a large accessible source of adult stem cells for both basic research and
clinical applications. Peripheral blood mononuclear cells (PBMCs) have been reported to …