Applying the Bradford Hill criteria for causation to repetitive head impacts and chronic traumatic encephalopathy

CJ Nowinski, SC Bureau, ME Buckland… - Frontiers in …, 2022 - frontiersin.org
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a
history of repetitive head impacts (RHI). CTE was described in boxers as early as the 1920s …

Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury

M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

Current understanding of neuroinflammation after traumatic brain injury and cell-based therapeutic opportunities

Y Xiong, A Mahmood, M Chopp - Chinese Journal of Traumatology, 2018 - mednexus.org
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide.
Increasing evidence indicates that TBI is an important risk factor for neurodegenerative …

Sleep-wake disturbances after traumatic brain injury: synthesis of human and animal studies

DK Sandsmark, JE Elliott, MM Lim - Sleep, 2017 - academic.oup.com
Sleep–wake disturbances following traumatic brain injury (TBI) are increasingly recognized
as a serious consequence following injury and as a barrier to recovery. Injury-induced sleep …

Applications of the Morris water maze in translational traumatic brain injury research

LB Tucker, AG Velosky, JT McCabe - Neuroscience & Biobehavioral …, 2018 - Elsevier
Acquired traumatic brain injury (TBI) is frequently accompanied by persistent cognitive
symptoms, including executive function disruptions and memory deficits. The Morris Water …

[HTML][HTML] Alcohol use disorder and traumatic brain injury

ZM Weil, JD Corrigan, K Karelina - Alcohol research: current …, 2018 - ncbi.nlm.nih.gov
Alcohol use and traumatic brain injury (TBI) are inextricably and bidirectionally linked.
Alcohol intoxication is one of the strongest predictors of TBI, and a substantial proportion of …

Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy

BD Semple, A Zamani, G Rayner, SR Shultz… - Neurobiology of …, 2019 - Elsevier
Survivors of traumatic brain injury (TBI) often develop chronic neurological, neurocognitive,
psychological, and psychosocial deficits that can have a profound impact on an individual's …

Sex matters: repetitive mild traumatic brain injury in adolescent rats

DK Wright, TJ O'Brien, SR Shultz… - Annals of clinical and …, 2017 - Wiley Online Library
Objective Whether sex differences contribute to the heterogeneity of mild traumatic brain
injury (mTBI) and repeated mTBI (Rm TBI) outcomes in adolescents is unknown. Therefore …

Models of traumatic brain injury-highlights and drawbacks

Q Zhao, J Zhang, H Li, H Li, F Xie - Frontiers in neurology, 2023 - frontiersin.org
Traumatic brain injury (TBI) is the leading cause for high morbidity and mortality rates in
young adults, survivors may suffer from long-term physical, cognitive, and/or psychological …

Inflammation in traumatic brain injury

TT Postolache, A Wadhawan, A Can… - Journal of …, 2020 - content.iospress.com
There is an increasing evidence that inflammation contributes to clinical and functional
outcomes in traumatic brain injury (TBI). Many successful target-engaging, lesion-reducing …