The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

Complex multicellular organisms require a coordinated response from multiple tissues to
maintain whole-body homeostasis in the face of energetic stressors such as fasting, cold …

Brown adipose tissue (BAT) stands out as the sole tissue able to substantially expend
energy by leveraging uncoupling protein 1 (UCP1) to increase proton permeability through …

Skeletal muscle, not adipose tissue, mediates cold-induced metabolic benefits | Nature
Metabolism Skip to main content Thank you for visiting nature.com. You are using a browser …

The discovery and rejuvenation of metabolically active brown adipose tissue (BAT) in adult
humans have offered a new approach to treating obesity and metabolic diseases. Beyond …

Mitochondria are required for energy production and even give brown adipose tissue (BAT)
its characteristic color due to their high iron content and abundance. The physiological …

Body weight is under physiological regulation. When body fat mass decreases, a series of
responses are triggered to promote weight regain by increasing food intake and decreasing …

Cachexia associated with chronic kidney disease (CKD) has been linked to GH resistance.
In CKD, GH treatment enhances muscular performance. We investigated the impact of GH …

White adipose tissue and brown adipose tissue (WAT and BAT) regulate fatty acid
metabolism and control lipid fluxes to other organs. Dysfunction of these key metabolic …